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    Article

    Exploratory aspirin resistance trial in healthy Japanese volunteers (J-ART) using platelet aggregation as a measure of thrombogenicity

    Aspirin prevents the production of thromboxane A2 (TXA2) by irreversibly inhibiting platelet cyclooxygenase, exhibiting antiplatelet actions. This agent has been reported to prevent relapse in patients with ische...

    T Fujiwara, M Ikeda, K Esumi, T D Fujita, M Kono in The Pharmacogenomics Journal (2007)

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    Separation of Enantiomers of Non-Protein Amino Acids by High-Performance Liquid Chromatography on a Chiral Ligand-Exchange Column

    The HPLC separation of enantiomers of underivatized non-protein amino acids was investigated by using a column packed with octadecylsilanized silica coated with N,S-dioctyl-D-penicillamine as a chiral ligand-exch...

    T. Miyazawa, H. Minowa, K. Imagawa, T. Yamada in Chromatographia (2004)

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    Combination treatment with interleukin-2 and interleukin-12 for murine renal cell carcinoma

    Background. We studied the anti-tumor effectiveness of treatment with interleukin-2 (IL-2) and/or IL-12 for a spontaneously arising murine renal cell carcinoma (RC-2). We also analyzed the immunological effects...

    T. Onishi, Y. Ohishi, H. Goto, K. Imagawa in International Journal of Clinical Oncology (1999)

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    Article

    Marked dependence on temperature of enantioselectivity in the Aspergillus oryzaeprotease-catalyzed hydrolysis of amino acid esters

    In the Aspergillus oryzae protease-catalyzed enantioselective hydrolysis of amino acid esters, linear relationships were observed between – RTln Eand T, where E= enantiomeric ratio and T= absolute temperature....

    T. Miyazawa, K. Imagawa, R. Yanagihara, T. Yamada in Biotechnology Techniques (1997)

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    Inhibition of Rabbit Gastric Epithelial Restoration by a Water Extract of Helicobacter Pylori: Evidence Using a Cultured Cell Model

    The detailed mechanism of H. pylori-induced gastric damage is still unknown. In this study, we showed that a water extract of H. pylori retarded the epithelial restoration in a cultured rabbit gastric epithelial ...

    N. Sato, S. Watanabe, X-E. Wang, M. Hirose in Cell Injury and Protection in the Gastroin… (1997)

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    Article

    Inhibition of rabbit gastric epithelial restoration by a water extract ofHelicobacter pylori: evidence using a cultured cell model

    The detailed mechanism ofH. pylori-induced gastric damage is still unknown. In this study, we showed that a water extract ofH. pylori retarded the epithelial restoration in a cultured rabbit gastric epithelial ce...

    N. Sato, S. Watanabe, X-E. Wang, M. Hirose, H. Oide, T. Kitamura in InflammoPharmacology (1996)

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    Patents And literature

    Robert J. Linhardt, A. Atkinson, C. Lowe in Applied Biochemistry and Biotechnology (1985)

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    Article

    Patents and literature

    Robert J. Linhardt, C. P. Bieber, F. D. Howard in Applied Biochemistry and Biotechnology (1985)

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    Correlative ontogenetic development of catecholamine- and LHRH-containing nerve endings in the median eminence of the rat

    The ontogenetic development of catecholamine (CA)-and LHRH-containing nerve endings in the median eminence of the rat was investigated by combining fluorescence histochemistry and immunohistochemistry in the s...

    Dr. Y. Ibata, N. Tani, H. L. Obata, M. Tanaka, S. Kubo in Cell and Tissue Research (1981)

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    The location of LH-RH neurons in the rat hypothalamus and their pathways to the median eminence

    The location of the perikarya of LH-RH neurons in the rat hypothalamus and their pathways to the median eminence were studied by immunohistochemistry and radioimmunoassay after placing stereotaxic electrolytic...

    Dr. Y. Ibata, K. Watanabe, H. Kinoshita, S. Kubo, Y. Sano in Cell and Tissue Research (1979)

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    Die Enzymausscheidung im Urin

    The origin of urinary enzymes is obscure. We therefore determined the levels of urinary, serum and kidney enzymes (lysozyme, amylase, alkaline phosphatase, glutamate transaminase, lactic dehydrogenase, leucine...

    M. Miyao, Y. Hasegawa, T. Kochi, Y. Yamagata, K. Imagawa in Zeitschrift für Kinderheilkunde (1972)

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    Die Enzymausscheidung im Urin

    The determination of serum enzyme levels has been increasingly used in diagnosis of children's diseases. However, urinary enzymes have been little studied and many problems remain to be elucidated.

    M. Miyao, Y. Hasegawa, T. Kochi, Y. Yamagata, K. Imagawa in Zeitschrift für Kinderheilkunde (1972)