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Article
Damage of cultured chondrocytes by hydrogen peroxide derived from polymorphonuclear leukocytes: a possible mechanism of cartilage degradation
To study the mechanisms of chondrocyte damage, chondrocyte cytotoxicity as shown by chromium-51 release induced by polymorphonuclear leukocytes (PMNLs) was examined. PMNLs significantly enhanced chondrocyte cy...
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Article
Cytokine enhancement of monocyte/synovial cell attachment to the surface of cartilage: a possible trigger of pannus formation in arthritis
When rheumatoid articular cartilage samples were incubated with normal peripheral blood monocytes and cultured synovial cells in the presence of recombinant human interleukin-1 (IL-1) in vitro, large numbers o...
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Article
Histopathology of femoral head osteonecrosis in rheumatoid arthritis: the relationship between steroid therapy and lipid degeneration in the osteocyte
To investigate the pathology of osteonecrosis of the femoral head (ON) in patients with rheumatoid arthritis (RA), we examined 26 hips clinically and histologically. In this study, we diagnosed ON by both the ...
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Chapter and Conference Paper
Arthrodesis of the Knee as a Salvage Procedure for Failed Total Knee Replacement
From 1973 to 1982, 30 patients underwent arthrodesis following failed total knee replacement at the Cleveland Clinic Foundation and Kobe University Hospital. The indication for arthrodesis was infection in 27,...
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Article
Dumbbell-shaped spinal extradural hemangioma
A case of recurrent extradural cavernous hemangioma is presented. In contrast to secondary extension of a vertebral hemangioma to the epidural space, pure epidural hemangioma is rare. The location of this case...
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Article
Interaction of polymorphonuclear leukocytes with calcium pyrophosphate dihydrate crystals deposited in chondrocalcinosis cartilage
Electron microscopy was used to investigate the characteristics of calcium pyrophosphate dihydrate (CPPD) crystals in chondrocalcinosis (pseudogout syndrome). Crystals in midzone cartilage were frequently seen...
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Article
An electron microscopic study of the synovial-bone junction in rheumatoid arthritis
The cellular characteristics of the rheumatoid synovial-bone junction (SBJ) were examined in the electron microscope. Large numbers of mononuclear inflammatory cells along the bone suggested the advance of the...
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Article
Bilateral peroneal nerve palsy secondary to posterior dislocation of the proximal tibiofibular joint in rheumatoid arthritis
Bilateral peroneal nerve palsy due to posterior dislocation of the proximal tibiofibular joint in a 72-year-old rheumatoid patient is described. Operative findings showed thickening of the synovial membrane of...
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Article
Inhibition of concanavalin A-induced phosphatidylinositol turnover and lysosomal enzyme release by cyclic AMP-elevating agents in rat peritoneal macrophages
When rat peritoneal macrophages were stimulated with concanavalin A (Con A), phosphatidylinositol (PI) turnover was rapidly induced and concomitantly N-acetylglucosaminidase was released. These two reactions w...
