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Article
Open AccessMap** the Theoretical Domain Framework to the Consolidated Framework for Implementation Research: do multiple frameworks add value?
Implementation researchers often combine the Theoretical Domain Framework (TDF) and Consolidated Framework for Implementation Research (CFIR) in their studies. However there is some debate on the merits of usi...
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Article
De novo vitamin D supplement use post-diagnosis is associated with breast cancer survival
Experimental laboratory data have indicated a protective effect of vitamin D on breast cancer progression, while epidemiological evidence is growing. Using pharmacy claims data, this study investigates the ass...
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Article
Emerging trends in hospitalisation for fragility fractures in Ireland
We analysed hospital admissions and bed occupancy for fragility fractures in Ireland over a 15-year period to assess fracture admission trends and to project admissions over the next three decades.
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Article
Impact of safety warnings on domperidone prescribing in Ireland
This study aimed to investigate the impact of the 2014 safety warnings on use of domperidone, on subsequent prescribing patterns in Ireland.
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Article
A retrospective cohort analysis of hypoglycaemic and cardiovascular agent use in young adults in the Irish primary care setting
The prevalence of type 2 diabetes in young adults is increasing, yet little is known about medication use in this population. This study aimed to describe hypoglycaemic and cardiovascular treatment patterns in...
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Article
On the same page: a novel interprofessional model of patient-centered perinatal consultation visits
To plan and implement an interprofessional collaborative care clinic for women in midwifery care needing a consultation with a maternal–fetal medicine specialist.
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Article
Open AccessImmunological efficacy of pneumococcal vaccine strategies in HIV-infected adults: a randomized clinical trial
The aim of this study was to compare the immunologic response to a prime-boost immunization strategy combining the 13-valent conjugate pneumococcal vaccine (PCV13) with the 23-valent polysaccharide pneumococca...
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Article
Generalisability of pharmacoepidemiological studies using restricted prescription data
Linking medication databases to disease registries enables population-based pharmacoepidemiology research. In Ireland, country-wide dispensing data is available only from the means-tested government-medical c...
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Article
The Impact of a Mindfulness-Based Stress Reduction Course (MBSR) on Well-Being and Academic Attainment of Sixth-form Students
There is a growing interest in develo** mindfulness skills in the context of education as a means to improve psychological well-being together with work-related skills and performance of children and adolesc...
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Article
Periconception HIV Risk Behavior Among Men and Women Reporting HIV-Serodiscordant Partners in KwaZulu-Natal, South Africa
HIV-infected men and women who choose to conceive risk infecting their partners. To inform safer conception programs we surveyed HIV risk behavior prior to recent pregnancy amongst South African, HIV-infected ...
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Article
Open AccessAntidepressant prescribing in Irish children: secular trends and international comparison in the context of a safety warning
In 2003, the Irish Medicines Board (IMB) warned against the treatment of childhood depression with selective serotonin reuptake inhibitors (SSRIs) due to increased risk of suicide. This study examined the effe...
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Article
Comorbidity, health-related quality of life and self-care in type 2 diabetes: a cross-sectional study in an outpatient population
Comorbid conditions may be related (concordant) or unrelated (discordant) to diabetes. Comorbidity in patients with type 2 diabetes (T2DM) is associated with reduced health-related quality of life (HRQoL) and ...
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Article
Regional variation in medication-taking behaviour of new users of oral anti-hyperglycaemic therapy in Ireland
Few studies have investigated regional variation in medication-taking behaviour. The purpose of this study was to investigate whether there are regional differences in non-persistence and non-adherence to oral...
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Article
Forget me not – the role of the general dental practitioner in dementia awareness
Argues that dental professionals are well placed to spot the early signs of dementia.
Stresses the importan...
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Article
Prescribing of antidiabetic therapies in Ireland: 10-year trends 2003–2012
Over the last decade there have been significant changes in the prescribing of antidiabetic therapies. It is of interest to know about these trends and variations in the Irish population so that future prescri...
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Article
Comparison of prescribing and adherence patterns of anti-osteoporotic medications post-admission for fragility type fracture in an urban teaching hospital and a rural teaching hospital in Ireland between 2005 and 2008
Poor adherence reduces the potential benefits of osteoporosis therapy, lowering gains in bone mineral density resulting in increased risk of fractures.
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Article
Feasibility and efficacy of a supervised exercise intervention in de-conditioned cancer survivors during the early survivorship phase: the PEACH trial
This study aims to evaluate the feasibility and efficacy of an 8-week supervised exercise program in de-conditioned cancer survivors within 2–6 months of chemotherapy completion.
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Article
Open AccessA nested case–control study of adjuvant hormonal therapy persistence and compliance, and early breast cancer recurrence in women with stage I–III breast cancer
Non-persistence and non-compliance are common in women prescribed hormonal therapy for breast cancer, but little is known about their influence on recurrence.
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Article
Hospitalisations for fracture and associated costs between 2000 and 2009 in Ireland: a trend analysis
In Ireland, the absolute numbers of hospitalisations for all osteoporotic-type fractures including hip fractures increased between 2000 and 2009 along with the mean length of stay. The cost of hospitalisations...
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Article
Patient profile in a bone health and osteoporosis prevention service in Ireland
To (1) characterise a cohort of patients attending a major osteoporosis clinic in Ireland and (2) examine the prescribing of preventative therapies amongst these patients.
