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Article
Development and characterization of a predictive microCT-based non-union model in Fischer F344 rats
Non-unions remain a clinical problem and are characterised by the failure to heal after a defined period of time. Current preclinical non-union models apply a wide variety of techniques to diminish intrinsic h...
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Article
Open AccessExploring the transformative potential of urban food
Urban food is a key lever for transformative change towards sustainability. While research reporting on the urban food practices (UFPs) in support of sustainability is increasing, the link towards transformati...
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Article
Open AccessIon milling: the perfect cross-section of a painted textile
The successful study and conservation of historical objects is greatly enhanced by accurate materials analysis. Here embedded cross-sections from a processional marching banner were viewed by scanning electron...
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Article
Developmentally appropriate care for adolescents and young adults with cancer: how well is Australia doing?
Developmentally appropriate care underpins quality cancer treatment. This study aimed to describe how well Australian cancer services deliver patient-focussed, developmentally appropriate care to adolescents a...
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Article
Open AccessBreaking down banners: analytical approaches to determining the materials of painted banners
This paper investigates a range of analytical techniques to yield information about the materials and processes used in making painted banners. A textile conservator, technical art historian and paintings cons...
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Article
Open AccessThe RNA binding protein HuR determines the differential translation of autism-associated FoxP subfamily members in the develo** neocortex
Forkhead-box domain (Fox) containing family members are known to play a role in neocorticogenesis and have also been associated with disorders on the autism spectrum. Here we show that a single RNA-binding pro...
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Article
Decoy receptors block TRAIL sensitivity at a supracellular level: the role of stromal cells in controlling tumour TRAIL sensitivity
Tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) is a death ligand cytokine known for its cytotoxic activity against malignantly transformed cells. TRAIL induces cell death through binding to d...
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Article
Clarifying nipple confusion
Nipple confusion, an infant’s difficulty with or preference for one feeding mechanism over another after exposure to artificial nipple(s), has been widely debated. This is in part due to conflicting statements...
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Article
Erratum to: Adolescents and young adult cancer survivors: exercise habits, quality of life and physical activity preferences
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Article
Adolescents and young adult cancer survivors: exercise habits, quality of life and physical activity preferences
Given the decades of survivorship for adolescent and young adult (AYA) cancer survivors, it is important to promote behaviours that enhance physical and mental well-being and quality of life (QoL). The purpose...
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Article
Inpatient diabetes care: complexity, resilience and quality of care
It is estimated that 10–15 % of UK hospital inpatients have diabetes. Poor glycemic control is a care quality problem that has been linked to organizational factors such as inadequate training, inadequate prot...
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Article
Identifying targets for the restoration and reactivation of BRM
Brahma (BRM) is a novel anticancer gene, which is frequently inactivated in a variety of tumor types. Unlike many anticancer genes, BRM is not mutated, but rather epigenetically silenced. In addition, histone ...
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Article
4.6: Anisotropy in solid breast lesions at shear wave elastography: relationship to the radial plane and implications for benign/malignant differentiation
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Article
Loss of PTEN induces microtentacles through PI3K-independent activation of cofilin
Loss of PTEN tumor suppressor enhances metastatic risk in breast cancer, although the underlying mechanisms are poorly defined. We report that homozygous deletion of PTEN in mammary epithelial cells induces tu...
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Article
Antigen receptor stereotypy across B-cell lymphoproliferations: the case of IGHV4-59/IGKV3-20 receptors with rheumatoid factor activity
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Article
Open AccessSingle-incision laparoscopic cholecystectomy
Single-incision laparoscopic surgery (SILS) has been proposed as a minimally invasive technique with the advantages of smaller external scars and reduced pain. Furthermore, usage of the flexible endoscope for ...
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Article
c-Src differentially regulates the functions of microtentacles and invadopodia
During metastasis, invading cells produce various actin-based membrane protrusions that promote directional migration and proteolysis of extracellular matrix (ECM). Observations of actin staining within thin, ...
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Article
Metastatic breast tumors express increased tau, which promotes microtentacle formation and the reattachment of detached breast tumor cells
The cytoskeletal organization of detached and circulating tumor cells (CTCs) is currently not well defined and may provide potential targets for new therapies to limit metastatic tumor spread. In vivo, CTCs reatt...
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Article
Open AccessInitial experience with transvaginal incisional hernia repair
Natural orifice surgery has evolved from a preclinical setting into a common occurrence at the University of California San Diego (UCSD). With close to 40 transvaginal cases, we have become comfortable with th...
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