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    Article

    Selective, efficient modulation of activated CD4+ αβT cells by the novel humanized antibody GZ-αβTCR targeting human αβTCR

    Allograft rejection and immunosuppression are two major issues in transplantation medicine. The specific targeting of alloreactive T cells, the initiators and promoters of allograft rejection, would be a promi...

    G Blank, C Welker, J Haarer, M Sterk, S Nadalin, V A C Yañez in Bone Marrow Transplantation (2015)

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    Article

    Generation, selection and preclinical characterization of an Fc-optimized FLT3 antibody for the treatment of myeloid leukemia

    The therapeutic efficacy of humanized or chimeric second-generation antitumor antibodies is clearly established, but often limited. In recent years, defined modifications of the glycosylation pattern or the am...

    M Hofmann, L Große-Hovest, T Nübling, E Pyż, M L Bamberg, S Aulwurm in Leukemia (2012)

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    Article

    A prospective comparison of immune reconstitution in pediatric recipients of positively selected CD34+ peripheral blood stem cells from unrelated donors vs recipients of unmanipulated bone marrow from related donors

    Positively selected CD34+ hematopoietic stem cells from unrelated donors (UD-HSCT) have been successfully transplanted, but little is known about immune reconstitution in this setting. Here we report a prospectiv...

    M Eyrich, C Leiler, P Lang, K Schilbach, M Schumm, P Bader in Bone Marrow Transplantation (2003)