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102 Result(s)
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Article
Approximate Bayesian computation analysis of EST-associated microsatellites indicates that the broadleaved evergreen tree Castanopsis sieboldii survived the Last Glacial Maximum in multiple refugia in Japan
Climatic changes have played major roles in plants’ evolutionary history. Glacial oscillations have been particularly important, but some of their effects on plants’ populations are poorly understood, includin...
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Article
Open AccessProspects for observing and localizing gravitational-wave transients with Advanced LIGO, Advanced Virgo and KAGRA
We present possible observing scenarios for the Advanced LIGO, Advanced Virgo and KAGRA gravitational-wave detectors over the next decade, with the intention of providing information to the astronomy community...
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Article
MOB1-YAP1/TAZ-NKX2.1 axis controls bronchioalveolar cell differentiation, adhesion and tumour formation
Mps One Binder Kinase Activator (MOB)1A/1B are core components of the Hippo pathway. These proteins, which coactivate LArge Tumour Suppressor homologue kinases, are also tumour suppressors. To investigate MOB1...
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Article
A subtype prediction score for primary aldosteronism
Primary aldosteronism (PA) is the most common cause of endocrine hypertension. Although adrenal venous sampling (AVS) is recommended as the gold standard procedure for subtype classification in PA, it is a spe...
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Chapter
Branched-chain amino acid-enriched snacks for sleep disturbance
Patients with liver cirrhosis (LC) have a variety of symptoms; some of them have sleep disturbance. The mechanism of sleep disturbance in these patients is still unclear. Sleep disturbance is one of the sympto...
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Article
Exacerbation of diabetic nephropathy by hyperlipidaemia is mediated by Toll-like receptor 4 in mice
Hyperlipidaemia is an independent risk factor for the progression of diabetic nephropathy, but its molecular mechanism remains elusive. We investigated in mice how diabetes and hyperlipidaemia cause renal lesi...
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Article
Induced pluripotent stem cells generated from diabetic patients with mitochondrial DNA A3243G mutation
The aim of this study was to generate induced pluripotent stem (iPS) cells from patients with mitochondrial DNA (mtDNA) mutation.
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Article
Nd/Ba substitution and oxygen deficiency effects on the pinning properties of NdBa2Cu3O7-σ single crystals
We studied the origin of peak effect in the magnetic field dependence of Jc in NdBa2Cu3O7-σ single crystals. The single crystals were grown by the slow cooling method under various partial O2 pressures(PO2) (0.04...
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Article
Electronic Properties of Silicon — M Binary Clusters (M = C & Na)
Electronic properties of silicon-carbon and silicon-sodium binary clusters, produced by laser vaporization, were investigated by photoelectron spectroscopic or photoionization spectroscopic method. The photoel...
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Article
Influence of N and Fe on α-Ti precipitation in the in situ TiC–titanium alloy composites
High strength with high ductility can be achieved in the titanium alloys by using metal precipitated ceramic particle as reinforcement. In this work, α + β or β-Ti alloy composites were prepared with α-Ti prec...
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Article
Angiotensin II type 1 receptor-independent beneficial effects of telmisartan on dietary-induced obesity, insulin resistance and fatty liver in mice
Evidence suggests that telmisartan, an angiotensin II type 1 receptor (AT1) blocker and peroxisome proliferator-activated receptor-γ partial agonist, has beneficial actions that limit development of the metabo...
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Article
Vortex glass scaling in Pb-doped Bi-2223 single crystal
We report on study of the vortex liquid in Pb-doped Bi-2223 single crystal using the in-plane resistivity measurements as a function of temperature and magnetic field up to 6 T applied perpendicular to CuO pla...
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Article
Beneficial effects of leptin on glycaemic and lipid control in a mouse model of type 2 diabetes with increased adiposity induced by streptozotocin and a high-fat diet
We have previously demonstrated the therapeutic usefulness of leptin in lipoatrophic diabetes and insulin-deficient diabetes in mouse models and could also demonstrate its dramatic effects on lipoatrophic diab...
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Chapter and Conference Paper
A new simple measurement system of visceral fat accumulation by bioelectrical impedance analysis
Measurement of visceral fat accumulation is essential for the diagnosis of obesity. Currently, the visceral fat area (VFA) obtained from the abdominal cross-sectional image measured by X-ray CT is used as the ...
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Article
Metabotropic glutamate receptor subtype-1 is essential for in vivo growth of melanoma
Ectopic expression of metabotropic glutamate receptor subtype 1 (mGluR1) in mouse melanocytes induces melanoma formation. Although requirement of mGluR1 for development of melanoma in the initial stage has bee...
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Article
Prevalence of interrelated autoantibodies in thyroid diseases and autoimmune disorders
Objective: We determined the autoantibody profile in autoimmune thyroid diseases (AITD) and examined the distribution of thyroid-related autoantibodies in other autoimmune disorders. Meth...
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Article
Chiasmal optic neuritis following mumps parotitis
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Article
Partial functional overlap of the three ras genes in mouse embryonic development
In mammals, three ras genes, H-ras, N-ras and K-ras, encode homologous but distinct 21-kDa Ras proteins. We examined the in vivo functional relationship of the three ras genes in mouse embryonic development by in...
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Article
Validation of the Japanese version of EORTC QLQ-CR38
The objective of this study was to test the reliability and validity of the Japanese version of the European Organization for Research and Treatment of Cancer (EORTC) Colorectal Cancer-Specific Quality of Life...
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Article
Upstream migration of adult chum and pink salmon in the Shibetsu River
The migratory behavior and swimming patterns of anadromous upstream migratory fish have been poorly described in the Shibetsu River in eastern Hokkaido, Japan. In this 2004 study, we used electromyogram (EMG) ...