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  1. Article

    Open Access

    Alagille-like syndrome with surprising karyotype: a case report

    Chromosome 5p partial monosomy (5p-syndrome) and chromosome 6p partial trisomy are chromosomal abnormalities that result in a variety of symptoms, but liver dysfunction is not normally one of them. Alagille sy...

    S. Amimoto, M. Ishii, K. Tanaka, S. Araki, M. Kuwamura… in Journal of Medical Case Reports (2023)

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  2. No Access

    Chapter and Conference Paper

    Channel and Basin Sedimentation Modelling Under Limited Data Availability: Case Study of a Port in Eastern Africa

    Since channel and basin sedimentation has an impact on the port operation, it is important to estimate future volume of the sedimentation appropriately at the planning stage of port development. However, the p...

    K. Kusuhara, M. Sakuraba, S. Onaka, S. Ichikawa, Y. Awazu in APAC 2019 (2020)

  3. No Access

    Article

    The efficacy of the direct clinical intervention for infectious diseases by a pediatric infectious disease specialist in the pediatric ward of a tertiary medical facility without a pediatric antimicrobial stewardship program

    Antimicrobial stewardship programs (ASPs) have been introduced in most hospital complexes; however, they are not always useful for pediatric patients. The aim of this study is to investigate the efficacy of di...

    T. Hoshina, N. Yamamoto, M. Ogawa… in European Journal of Clinical Microbiology … (2017)

  4. No Access

    Article

    BTK gene targeting by homologous recombination using a helper-dependent adenovirus/adeno-associated virus hybrid vector

    X-linked agammaglobulinemia (XLA) is one of the most common humoral immunodeficiencies, which is caused by mutations in Bruton’s tyrosine kinase (BTK) gene. To examine the possibility of using gene therapy for XL...

    H Yamamoto, M Ishimura, M Ochiai, H Takada, K Kusuhara, Y Nakatsu… in Gene Therapy (2016)

  5. No Access

    Article

    Identification of bacterial pathogens in pediatric community-acquired lower respiratory tract infection using a simplified procedure of sputum sampling and examination: comparison between hospitalized children with and without underlying diseases

    The aim of this study is to confirm the usefulness of sputum sampling from the hypopharynx through the nose to identify causative bacteria of pediatric community-acquired lower respiratory tract infection (CA-...

    T. Hoshina, K. Kusuhara, T. Takimoto… in European Journal of Clinical Microbiology … (2010)

  6. No Access

    Article

    Recombinant Sendai virus provides a highly efficient gene transfer into human cord blood-derived hematopoietic stem cells

    Hematopoietic stem cells (HSCs) are a promising target for gene therapy, however, the low efficiencies of gene transfer using currently available vectors face practical limitations. We have recently developed ...

    C H **, K Kusuhara, Y Yonemitsu, A Nomura, S Okano, H Takeshita… in Gene Therapy (2003)

  7. No Access

    Article

    Lack of association between atopic asthma and polymorphisms of the histamine H1 receptor, histamine H2 receptor, and histamine N-methyltransferase genes

    Y. Sasaki, K. Ihara, S. Ahmed, K. Yamawaki, K. Kusuhara, Hideki Nakayama… in Immunogenetics (2000)

  8. No Access

    Article

    Water and electrolyte balance after ileal J pouch-anal anastomosis in ulcerative colitis and familial adenomatous polyposis

    The water and electrolyte balance was studied in 31 patients with ulcerative colitis (UC) and 22 with familial adenomatous polyposis (FAP) who underwent staged surgery involving colectomy and ileal J pouch-ana...

    T. Okamoto, M. Kusunoki, K. Kusuhara… in International Journal of Colorectal Disease (1995)

  9. No Access

    Article

    Reduction of the effluent volume in high-output ileostomy patients by a somatostatin analogue, SMS 201-995

    Twelve ileostomy patients were given subcutaneous SMS 201-995 therapy (100 μg t.d.s. for 5 days) in a randomized placebo-controlled trial. All patients had ileostomies constructed 60 cm proximal to the termina...

    K. Kusuhara, M. Kusunoki, T. Okamoto… in International Journal of Colorectal Disease (1992)

  10. No Access

    Chapter

    Analysis of luteal insufficiency in infertile women

    The endocrinological status of luteal insufficiency has been analysed and then classified into types by hormonal profile.

    K. Kusuhara, K. Matsumoto, T. Nakajima, T. Ootaka, M. Shoji… in Ovulation and its Disorders (1984)