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IKZF1 deletion is enriched in pediatric B-cell precursor acute lymphoblastic leukemia patients showing prednisolone resistance

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  1. Article

    Open Access

    Characterization of pediatric Philadelphia-negative B-cell precursor acute lymphoblastic leukemia with kinase fusions in Japan

    Recent studies revealed that a substantial proportion of patients with high-risk B-cell precursor acute lymphoblastic leukemia (BCP-ALL) harbor fusions involving tyrosine kinase and cytokine receptors, such as AB...

    T Imamura, N Kiyokawa, M Kato, C Imai, Y Okamoto, M Yano, K Ohki… in Blood Cancer Journal (2016)

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  2. Article

    Open Access

    Markedly improved outcomes and acceptable toxicity in adolescents and young adults with acute lymphoblastic leukemia following treatment with a pediatric protocol: a phase II study by the Japan Adult Leukemia Study Group

    The superiority of the pediatric protocol for adolescents with acute lymphoblastic leukemia (ALL) has already been demonstrated, however, its efficacy in young adults remains unclear. The ALL202-U protocol was...

    F Hayakawa, T Sakura, T Yujiri, E Kondo, K Fujimaki, O Sasaki… in Blood Cancer Journal (2014)

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  3. Article

    Open Access

    Prognostic implications of CEBPA mutations in pediatric acute myeloid leukemia: a report from the Japanese Pediatric Leukemia/Lymphoma Study Group

    CCAAT/enhancer-binding protein alpha (CEBPA) mutations are a favorable prognostic factor in adult acute myeloid leukemia (AML) patients; however, few studies have examined their significance in pediatric AML pati...

    H Matsuo, M Kajihara, D Tomizawa, T Watanabe, A M Saito, J Fujimoto… in Blood Cancer Journal (2014)

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