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  1. No Access

    Article

    LKB1 inhibits HPV-associated cancer progression by targeting cellular metabolism

    Liver kinase B1 (LKB1) is mutationally inactivated in Peutz–Jeghers syndrome and in a variety of cancers including human papillomavirus (HPV)-caused cervical cancer. However, the significance of LKB1 mutations...

    Q Zeng, J Chen, Y Li, K D Werle, R-X Zhao, C-S Quan, Y-S Wang, Y-X Zhai… in Oncogene (2017)

  2. No Access

    Article

    LKB1 reduces ROS-mediated cell damage via activation of p38

    Liver kinase B1 (LKB1, also known as serine/threonine kinase 11, STK11) is a tumor suppressor mutated in Peutz–Jeghers syndrome and in a variety of sporadic cancers. Herein, we demonstrate that LKB1 controls t...

    H-G Xu, Y-X Zhai, J Chen, Y Lu, J-W Wang, C-S Quan, R-X Zhao, X **ao, Q He… in Oncogene (2015)

  3. Article

    Open Access

    Piperlongumine induces autophagy by targeting p38 signaling

    Piperlongumine (PL), a natural product isolated from the plant species Piper longum L., can selectively induce apoptotic cell death in cancer cells by targeting the stress response to reactive oxygen species (...

    Y Wang, J-W Wang, X **ao, Y Shan, B Xue, G Jiang, Q He, J Chen… in Cell Death & Disease (2013)

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