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Article
Measurement of adherence and health-related quality of life during anticoagulation therapy in cancer-associated venous thromboembolism (VTE): a multicenter quantitative study
Therapy for cancer-associated venous thromboembolism (VTE) includes long-term anticoagulation, which may have substantial impact on the health-related quality of life (HRQL) of patients. We assessed patient-re...
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Article
Open AccessA randomized phase III study of pretransplant conditioning for AML/MDS with fludarabine and once daily IV busulfan ± clofarabine in allogeneic stem cell transplantation
Pretransplant conditioning with Fludarabine (Flu)-Busulfan (Bu) is safe, but clofarabine (Clo) has improved antileukemic activity. Hypothesis: Flu+Clo-Bu (FCB) yields superior progression-free survival (PFS) a...
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Article
KRD vs. VRD as induction before autologous hematopoietic progenitor cell transplantation for high-risk multiple myeloma
Bortezomib, lenalidomide, and dexamethasone (VRD) induction is standard prior to autologous hematopoietic cell transplantation (auto-HCT) in newly diagnosed, high-risk multiple myeloma (ND-HRMM). Carfilzomib (...
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Article
Open AccessPIONEER-Panc: a platform trial for phase II randomized investigations of new and emerging therapies for localized pancreatic cancer
Personalized and effective treatments for pancreatic ductal adenocarcinoma (PDAC) continue to remain elusive. Novel clinical trial designs that enable continual and rapid evaluation of novel therapeutics are n...
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Article
Enhanced anchoring and catalytic conversion of polysulfides by iron phthalocyanine for graphene-based Li–S batteries
Rechargeable lithium–sulfur (Li–S) batteries are seriously limited by low sulfur utilization and sluggish electrochemical reaction activity of polysulfide intermediates exacerbated by the detrimental shuttle e...
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Article
Open AccessSimplified molecular classification of lung adenocarcinomas based on EGFR, KRAS, and TP53 mutations
Gene expression profiling has consistently identified three molecular subtypes of lung adenocarcinoma that have prognostic implications. To facilitate stratification of patients with this disease into similar ...
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Chapter and Conference Paper
Modelling and Simulation of an Electric Trimmable Horizontal Stabilizer Actuator Based on Bond Graph
The trimmable horizontal stabilizer actuator (THSA) is a key part of the aircraft flight control system. This paper focuses on the new electrical type of THSA. System structure and control scheme are firstly i...
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Article
Open AccessCorrection to: Infliximab associated with faster symptom resolution compared with corticosteroids alone for the management of immune-related enterocolitis
Following publication of the original article [1], the authors reported an error in their listed affiliations.
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Article
Open AccessAtypical plant homeodomain of UBR7 functions as an H2BK120Ub ligase and breast tumor suppressor
The roles of Plant Homeodomain (PHD) fingers in catalysis of histone modifications are unknown. We demonstrated that the PHD finger of Ubiquitin Protein Ligase E3 Component N-Recognin7 (UBR7) harbors E3 ubiqui...
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Article
Open AccessInfliximab associated with faster symptom resolution compared with corticosteroids alone for the management of immune-related enterocolitis
Immune-related enterocolitis (irEC) is the most common serious complication from checkpoint inhibitors (CPIs). The current front-line treatment for irEC, high-dose corticosteroids (CS), have significant side e...
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Article
Adjuvant versus neoadjuvant chemotherapy in triple-negative breast cancer patients with BRCA mutations
As triple-negative breast cancers are associated with earlier recurrences and poorer survival, optimal treatment of early-stage breast cancer is essential. Several retrospective studies in triple-negative brea...
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Article
Vegetation pattern in shell ridge island in China’s Yellow River Delta
In general, coastal habitat conditions are extremely harsh, with the ecological equilibrium inextricably related to the plant community. Understanding the natural vegetation features of a coastal zone with lit...