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Article
Open AccessDevelopment and preliminary validation of a prediction formula of sodium and sodium-to-potassium ratio based on multiple regression using 24-h urines
Accurate measurement of sodium intake in the diet is challenging, and epidemiological studies can be hampered by the attenuation of associations due to measurement error in sodium intake. A prediction formula ...
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Article
Reproducibility and dietary correlates of plasma polyphenols in the JPHC-NEXT Protocol Area study
In recent years, an increasing number of epidemiological studies have suggested a role of polyphenols in the prevention of chronic diseases. Prospective cohort studies have typically measured polyphenol concen...
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Article
Open AccessAssociations between dairy intake and mortality due to all-cause and cardiovascular disease: the Japan Public Health Center-based prospective study
Some studies have investigated the relation between dairy products and mortality, but with inconsistent results.
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Article
Open AccessProspective study of dietary changes in cancer survivors for five years including pre- and post- diagnosis compared with those in cancer-free participants
The number of long-term survivors after a cancer diagnosis is increasing. Few investigations have compared survivors’ diets to their original pre-diagnosis dietary pattern or with the patterns of cancer-free c...
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Article
Open AccessAssociation between irregular daily routine and risk of incident stroke and coronary heart disease in a large Japanese population
Circadian misalignments have been linked to adverse cardiometabolic outcomes. However, the association between irregular daily routine and the risk of cardiovascular disease (CVD) remains unknown. We examined ...
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Article
Validity of dietary isothiocyanate intake estimates from a food frequency questionnaire using 24 h urinary isothiocyanate excretion as an objective biomarker: the JPHC-NEXT protocol area
Isothiocyanate (ITC) is formed via the hydrolysis of glucosinolates by myrosinase, found in cruciferous vegetables. Although myrosinase is inactivated by the cooking process, no studies have incorporated the e...
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Article
Dietary glycemic index, glycemic load and mortality: Japan Public Health Center-based prospective study
Long-term associations of dietary glycemic index (GI) and glycemic load (GL) with mortality outcomes remain unclear.
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Article
Open AccessSugary drink consumption and risk of kidney and bladder cancer in Japanese adults
Globally, sugary drinks are widely consumed, however, few epidemiologic studies have investigated the association between sugary drink consumption and risk of kidney and bladder cancer. We examined the associa...
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Article
Comparison between the impact of fermented and unfermented soy intake on the risk of liver cancer: the JPHC Study
The aim of this study was to compare the impact of fermented and unfermented soy intake, based on the following soy-derived products: tofu, soymilk, natto, and miso, on the risk of liver cancer among Japanese ...
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Article
Associations between changes in fruit and vegetable consumption and weight change in Japanese adults
Fruits and vegetables may induce greater satiety, reduce hunger, decrease energy intake, and modulate energy metabolism, thereby playing a role in weight loss.
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Article
Open AccessVariations in the estimated intake of acrylamide from food in the Japanese population
Due to concerns of carcinogenicity, it is necessary to assess long-term acrylamide exposure in individuals. Whether the available methods of estimating acrylamide intake can indicate long-term exposure remains...
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Article
Effect of monitoring salt concentration of home-prepared dishes and using low-sodium seasonings on sodium intake reduction
Objective methods such as the monitoring of salt concentrations in home-prepared dishes may be effective in reducing salt intake. We investigated the effect of monitoring the salt concentration of home-prepare...
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Article
Dietary patterns and prostate cancer risk in Japanese: the Japan Public Health Center-based Prospective Study (JPHC Study)
The development of prostate cancer may be impacted by environmental factors, including diet. The aim of this study was to evaluate the association between dietary patterns and risk of prostate cancer in a larg...
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Article
Dietary fiber intake and risk of breast cancer defined by estrogen and progesterone receptor status: the Japan Public Health Center-based Prospective Study
Epidemiological studies have suggested a protective effect of dietary fiber intake on breast cancer risk while the results have been inconsistent. Our study aimed to investigate the association between dietary...
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Article
Glycemic index and glycemic load and risk of colorectal cancer: a population-based cohort study (JPHC Study)
The aim of this study was for the first time to assess the association between glycemic index (GI), glycemic load (GL), and colorectal cancer using a prospective Japanese population-based cohort.
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Article
Validity of a self-administered food frequency questionnaire in the estimation of heterocyclic aromatic amines
Clarification of the putative etiologic role of heterocyclic aromatic amines (HAAs) in the development of cancer requires a validated assessment tool for dietary HAAs. This study primarily aimed to evaluate th...
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Article
Open AccessUse of vitamin supplements and risk of total cancer and cardiovascular disease among the Japanese general population: A population-based survey
Despite the popular use of vitamin supplements and several prospective cohort studies investigating their effect on cancer incidence and cardiovascular disease (CVD), scientific data supporting their benefits ...
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Article
Dietary isoflavone intake and breast cancer risk in case–control studies in Japanese, Japanese Brazilians, and non-Japanese Brazilians
Although epidemiologic studies have shown an inverse association between isoflavones and breast cancer risk, little evidence for a dose–response relation is available. We conducted hospital-based case–control ...
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Article
Open AccessValidity of a self-administered food frequency questionnaire (FFQ) and its generalizability to the estimation of dietary folate intake in Japan
In an epidemiological study, it is essential to test the validity of the food frequency questionnaire (FFQ) for its ability to estimate dietary intake. The objectives of our study were to 1) validate a FFQ for...
