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  1. Article

    Open Access

    Novel candidate drugs in anti-tumor necrosis factor refractory Crohn’s diseases: in silico study for drug repositioning

    Biologicals like anti-tumor necrosis factor (TNF) therapy for Crohn’s disease (CD) are safe and effective but there is a significant rate of primary and secondary nonresponse in the patients. In this study, we...

    Min Seob Kwak, Hun Hee Lee, Jae Myung Cha, Hyun Phil Shin… in Scientific Reports (2020)

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  2. No Access

    Article

    Probiotics Ameliorate Stool Consistency in Patients with Chronic Constipation: A Randomized, Double-Blind, Placebo-Controlled Study

    The efficacy of probiotics for improving clinical symptoms, altering the fecal microbiota, and regulating serum immune cytokine levels was investigated in patients with irritable bowel syndrome-constipation (I...

    ** Young Yoon, Jae Myung Cha, Ju Kyoung Oh, Pei Lei Tan… in Digestive Diseases and Sciences (2018)

  3. Article

    Open Access

    Evaluation of scoring systems without endoscopic findings for predicting outcomes in patients with upper gastrointestinal bleeding

    Risk scoring systems are used to evaluate patients with upper gastrointestinal bleeding (UGIB). We compared Glasgow-Blatchford score (GBS), modified GBS (mGBS), and Pre-endoscopy Rockall score (Pre-E RS) for i...

    Il-Gyu Ko, Sung-Eun Kim, Bok Soon Chang, Min Seob Kwak… in BMC Gastroenterology (2017)

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  4. No Access

    Article

    Successful Endoscopic Hemostasis Is a Protective Factor for Rebleeding and Mortality in Patients with Nonvariceal Upper Gastrointestinal Bleeding

    Rebleeding and mortality rates remain high in patients with nonvariceal upper gastrointestinal bleeding.

    Yong Jae Han, Jae Myung Cha, Jae Hyun Park… in Digestive Diseases and Sciences (2016)

  5. No Access

    Article

    Predictive Factors for Endoscopic Visibility and Strategies for Pre-endoscopic Prokinetics Use in Patients with Upper Gastrointestinal Bleeding

    Although current guideline recommends selective use of pre-endoscopic prokinetics to increase diagnostic yield in upper gastrointestinal bleeding (UGIB) patients, no data to guide the use of these drugs are av...

    Jun Uk Lim, Jae Jun Park, Young Hoon Youn, Sunyong Kim… in Digestive Diseases and Sciences (2015)

  6. No Access

    Article

    The risk of postpolypectomy bleeding during colonoscopy in patients with early liver cirrhosis

    Colonoscopists are often hesitant to perform endoscopic polypectomy in patients with liver cirrhosis (LC) because of the risk for postpolypectomy bleeding (PPB). However, little is known about the risk of PPB ...

    Jung Won Jeon, Hyun Phil Shin, Joung Il Lee, Kwang Ro Joo… in Surgical Endoscopy (2012)

  7. No Access

    Article

    Efficacy of Entecavir and Adefovir Combination Therapy for Patients with Lamivudine- and Entecavir-Resistant Chronic Hepatitis B

    The optimal treatment of patients with chronic hepatitis B (CHB) who develop resistance to both lamivudine (LMV) and entecavir (ETV) after sequential monotherapy of LMV and ETV remains little known.

    Jung Won Jeon, Hyun Phil Shin, Joung Il Lee… in Digestive Diseases and Sciences (2012)

  8. No Access

    Article

    Early Use of Needle-Knife Fistulotomy Is Safe in Situations Where Difficult Biliary Cannulation Is Expected

    Difficult cannulation is a well known risk for post-ERCP pancreatitis. This study evaluated the outcomes of needle-knife fistulotomy (NKF) used prior to being faced with difficult biliary cannulation.

    Jun Uk Lim, Kwang Ro Joo, Jae Myung Cha, Hyun Phil Shin… in Digestive Diseases and Sciences (2012)

  9. No Access

    Article

    Flexible Spectral Imaging Color Enhancement (FICE) Is Useful to Discriminate Among Non-neoplastic Lesion, Adenoma, and Cancer of Stomach

    Studies regarding the discrimination of non-neoplastic lesion, adenoma, and cancer of the stomach using magnifying endoscopy with flexible spectral imaging color enhancement system (FIME) in each different cha...

    Sung Won Jung, Kyu Seong Lim, Jun Uk Lim, Jung Won Jeon… in Digestive Diseases and Sciences (2011)