5 Result(s)
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Article
Open AccessElucidating the characteristics of Mx1 and resistance to influenza A virus subtype H1N1 in the newly developed KWM/Hym mice
Inbred mice have several advantages, including genetic similarity to humans, a well-established gene manipulation system, and strong tolerance to inbreeding. However, inbred mice derived from a limited genetic...
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Open AccessGenetic and morphometric characteristics of Korean wild mice (KWM/Hym) captured at Chuncheon, South Korea
Laboratory inbred mice are used widely and commonly in biomedical research, but inbred mice do not have a big enough gene pool for the research. In this study, genetic and morphometric analyses were performed ...
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Article
Open AccessOver-expression of myosin7A in cochlear hair cells of circling mice
Circling mouse (C57BL/6J-cir/cir) deleted the transmembrane inner ear (Tmie) gene is an animal model for human non-syndromic recessive deafness, DFNB6. In circling mouse, hair cells in the cochlea have degenerate...
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Open AccessErratum to: Rapid and efficient identification of the mouse leptin receptor mutation (C57BLKS/J-Leprdb) by tetra-primer amplification refractory mutation system-polymerase chain reaction (ARMS-PCR) analysis
We designed 4 primers for amplification of allelespecific PCR products from leptin receptor mutant and normal alleles using primer design web service for tetraprimer ARMS-PCR (Figure 1) i.e., Lepr-forward oute...
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Article
Open AccessRapid and efficient identification of the mouse leptin receptor mutation (C57BL/KsJ-db/db) by tetra-primer amplification refractory mutation system-polymerase chain reaction (ARMS-PCR) analysis
The C57BLKS/J-Leprdb mouse has a point mutation in the leptin receptor gene and is one of the most useful animal model for non-insulin dependent diabetes mellitus in human. Since the homozygote of C57BLKS/J-Leprd...
