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Article
Preparation of bifunctional electrocatalyst by recycling heavy metal ions from wastewater using EDTAD-functionalized MOF as highly efficient adsorbent
The recovery and subsequent reuse of heavy metal ions from industrial wastewater are crucial for promoting sustainable development, but they also present significant challenges. In this article, ethylenediamin...
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Article
RNA m6A methylation and regulatory proteins in pulmonary arterial hypertension
m6A (N6‑methyladenosine) is the most common and abundant apparent modification in mRNA of eukaryotes. The modification of m6A is regulated dynamically and reversibly by methyltransferase (writer), demethylase ...
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Article
Frizzled receptors (FZDs) in Wnt signaling: potential therapeutic targets for human cancers
Frizzled receptors (FZDs) are key contributors intrinsic to the Wnt signaling pathway, activation of FZDs triggering the Wnt signaling cascade is frequently observed in human tumors and intimately associated w...
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Article
Open AccessRetraction Note: Exosomal lncRNA HNF1A-AS1 affects cisplatin resistance in cervical cancer cells through regulating microRNA-34b/TUFT1 axis
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Article
Open AccessSerum LDL Promotes Microglial Activation and Exacerbates Demyelinating Injury in Neuromyelitis Optica Spectrum Disorder
Neuromyelitis optica spectrum disorder (NMOSD) is an autoimmune inflammatory demyelinating disease of the central nervous system (CNS) accompanied by blood-brain barrier (BBB) disruption. Dysfunction in microg...
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Chapter and Conference Paper
Design of Noise Reduction Structure of Porous Muffler Based on Ant Colony Algorithm
The design of noise reduction structure plays an important role in porous mufflers, but there is the problem of inaccurate noise reduction positioning. The traditional decision tree algorithm cannot solve the ...
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Chapter and Conference Paper
A New Method of Noise Spectrum Technology to Identify Reservoir Flow Profile
Traditional production logging (PLT) is limited by the casing or completion strings and can’t represent the flow behind the casing or flow in the reservoir. Noise spectrum logging technology (NTO) measures the...
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Chapter and Conference Paper
Field Application of Switchgear Abnormal Noise Detection Based on Acoustic Imaging Technology
In order to realize the non-contact acoustic imaging location and identification of switchgear abnormal noise type, this paper mainly combines three cases of abnormal noise defect caused by mechanical loosenes...
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Chapter and Conference Paper
Investigation and Analysis of Hidden Danger in a 220kV GIS Isolation Switch
This paper takes an example of a partial discharge online monitoring system discovering suspended discharge signals inside GIS. Firstly, the presence of internal discharge is determined through SF6 gas compositio...
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Article
Open AccessCytotoxic phenazine and antiallergic phenoxazine alkaloids from an arctic Nocardiopsis dassonvillei SCSIO 502F
Microbes well-adapted to the Arctic Ocean are promising for producing novel compounds, due to their fancy strategies for adaptation and being under-investigated. Two new phenazine alkaloids (1 and 2) and one new ...
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Article
Metal–organic frameworks modified melamine foam in pipette-tip for rapid solid-phase extraction of organophosphorus pesticides in fruits and vegetables
In this work, metal–organic frameworks (MOFs) including Fe-MIL-101 and Ti-MIL-125 were prepared and fixed on the melamine foam (MF) by polyvinylidene fluoride (PVDF) to prepare MF/PVDF/MOFs, which was used as ...
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Article
Differences in Non-suicidal Self-injury Behaviors between Unipolar Depression and Bipolar Depression in Adolescent Outpatients
Non-suicidal self-injury (NSSI) has a higher prevalence in adolescents with depressive disorders than in community adolescents. This study examined the differences in NSSI behaviors between adolescents with un...
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Article
Constrained C2 adsorbate orientation enables CO-to-acetate electroreduction
The carbon dioxide and carbon monoxide electroreduction reactions, when powered using low-carbon electricity, offer pathways to the decarbonization of chemical manufacture1,2. Copper (Cu) is relied on today for c...
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Article
Design, synthesis, and evaluation of 2,2’-bipyridyl derivatives as bifunctional agents against Alzheimer’s disease
Alzheimer’s disease (AD) is a complex multifactorial neurodegenerative disease. Metal ion dyshomeostasis and Aβ aggregation have been proposed to contribute to AD progression. Metal ions can bind to Aβ and pro...
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Article
Open AccessTREM2 deficiency inhibits microglial activation and aggravates demyelinating injury in neuromyelitis optica spectrum disorder
Neuromyelitis optica spectrum disorder (NMOSD) is an inflammatory demyelinating disorder of the central nervous system (CNS) triggered by autoimmune mechanisms. Microglia are activated and play a pivotal role ...
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Article
Genetic structure, major chemical component contents and agronomic characters of the principal cultivars of the kelp Saccharina japonica in the largest kelp production province in China
The big success of farming the kelp Saccharina japonica in China is partly due to the transplantation of this cold water species to the subtropical Fujian province since the 1950s. After more than 70 year’s devel...
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Article
A review of the current research on in vivo and in vitro detection for alpha-synuclein: a biomarker of Parkinson’s disease
Parkinson’s disease is a health-threatening neurodegenerative disease of the elderly with clinical manifestations of motor and non-motor deficits such as tremor palsy and loss of smell. Alpha-synuclein (α-Syn)...
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Article
Role of α-synuclein in microglia: autophagy and phagocytosis balance neuroinflammation in Parkinson’s disease
Parkinson’s disease (PD) is the second most common neurodegenerative disease, and is characterized by accumulation of α-synuclein (α-syn). Neuroinflammation driven by microglia is an important pathological man...
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Article
Open AccessRole of antiangiogenic agents in first-line treatment for advanced NSCLC in the era of immunotherapy
“Anti-angiogenetic drugs plus chemotherapy” (anti-angio-chemo) and “immune checkpoint inhibitors plus chemotherapy” (ICI-chemo) are superior to traditional chemotherapy in the first-line treatment of patients ...
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Article
Open AccessAnti-BCMA CAR T-cell therapy CT103A in relapsed or refractory AQP4-IgG seropositive neuromyelitis optica spectrum disorders: phase 1 trial interim results
Chimeric antigen receptor (CAR) T-cell therapy that targets B-cell maturation antigen (BCMA) have great potentials in autoimmune diseases and could be novel therapeutics for relapsed/refractory neuromyelitis o...
