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Article
The Genome of the Marine Rotifer Brachionus manjavacas: Genome-Wide Identification of 310 G Protein-Coupled Receptor (GPCR) Genes
The marine rotifer Brachionus manjavacas is widely used in ecological, ecotoxicological, and ecophysiological studies. The reference genome of B. manjavacas is a good starting point to uncover the potential molec...
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Article
Effects of zinc and mercury on ROS-mediated oxidative stress-induced physiological impairments and antioxidant responses in the microalga Chlorella vulgaris
The rapid growth of industrialization and urbanization results in deterioration of freshwater systems around the world, rescinding the ecological balance. Among many factors that lead to adverse effects in aqu...
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Article
Targeted cytochrome P450 3045C1 (CYP3045C1) gene mutation via CRISPR-Cas9 ribonucleoproteins in the marine rotifer Brachionus koreanus
The CRISPR-Cas9 system has revolutionized genetic engineering and has been applied in numerous model organisms to date. To examine the capacity of the CRISPR-Cas9 system for generation of mutants in the marine...
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Article
Effects of temperature shifts on life parameters and expression of fatty acid synthesis and heat shock protein genes in temperate and Antarctic copepods Tigriopus japonicus and Tigriopus kingsejongensis
Global warming, increase of the atmospheric temperature leading to changes in climate, is a growing environmental concern for all organisms including marine organisms, and many efforts have been made to reveal...
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Article
Comparison of long-term clinical outcomes between endoscopic and surgical resection for early-stage adenocarcinoma of the esophagogastric junction
The aim of this study was to analyze long-term clinical and oncologic outcomes in patients with early-stage adenocarcinoma of the esophagogastric junction (AEG) managed with either endoscopic resection (ER) or...
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Article
Long-term outcomes of endoscopic submucosal dissection in comparison to surgery in undifferentiated-type intramucosal gastric cancer using propensity score analysis
The treatment of intramucosal early gastric cancer with undifferentiated-type histologies (UD-EGCs) using endoscopic submucosal dissection (ESD) is controversial. This study aimed to compare the clinical and o...
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Article
Open AccessAging extension and modifications of lipid metabolism in the monogonont rotifer Brachionus koreanus under chronic caloric restriction
To examine the interrelationship of aging extension and modification of lipid metabolism under chronic caloric restriction (CCR; reduced concentration of the green algae Tetraselmis suecica) in the monogonont rot...
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Chapter
Image Magnification Endoscopy
Image magnification endoscopy is defined by the capacity to perform optical zoom by adjusting the position of the movable lens at the tip of the endoscope. Optical zoom endoscopes can magnify images up to 150 ...
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Article
Comparative study between endoscopic submucosal dissection and surgery in patients with early gastric cancer
Endoscopic submucosal dissection (ESD) is accepted as a standard treatment in patients with early gastric cancer (EGC) who have a negligible risk of lymph node metastasis. The aim of this study was to compare ...
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Article
Effects of temperature on growth and fatty acid synthesis in the cyclopoid copepod Paracyclopina nana
We have used the cyclopoid copepod Paracyclopina nana to understand responses to the temperature shift. To determine the changes of molecular mechanisms, which would lead to physiological changes in P. nana, we i...
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Article
Additive treatment improves survival in elderly patients after non-curative endoscopic resection for early gastric cancer
Endoscopic resection (ER) is accepted as a curative treatment option for selected cases of early gastric cancer (EGC). Although additional surgery is often recommended for patients who have undergone non-cura...
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Article
Clinical outcomes of and management strategy for perforations associated with endoscopic submucosal dissection of an upper gastrointestinal epithelial neoplasm
Perforation is one of the major complications of endoscopic submucosal dissection (ESD). In the present study, we investigated the clinical outcomes of and management strategies for ESD-related perforations.
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Article
A specific role of endoscopic ultrasonography for therapeutic decision-making in patients with gastric cardia cancer
The role of endoscopic ultrasonography (EUS) in gastric cardia cancer should be further evaluated because the accuracy of EUS depends on tumor location. We aimed to identify a specific role of EUS for therapeu...
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Article
Is the recent WHO histological classification for gastric cancer helpful for application to endoscopic resection?
Endoscopic resection is performed in undifferentiated-type early gastric cancer (UD-EGC), including poorly differentiated (PD) adenocarcinoma and signet ring cell (SRC) carcinoma. We previously found that diff...
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Article
The new modified ABCD method for gastric neoplasm screening
The ABCD screening method was developed for risk stratification of gastric cancer. It is unclear whether the ABCD method can predict the risk of gastric neoplasms, including gastric adenomas, as observed for g...
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Article
Safety and feasibility of simultaneous endoscopic submucosal dissection for multiple gastric neoplasias
Synchronous gastric neoplasms are not infrequently detected, thus endoscopic submucosal dissection (ESD) for multiple early gastric neoplasia is occasionally considered. However, there have been few investigat...
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Article
Early gastric cancer with mixed histology predominantly of differentiated type is a distinct subtype with different therapeutic outcomes of endoscopic resection
Safety of endoscopic resection (ER) for early gastric cancers (EGC) with mixed histology predominantly of differentiated type has not been securely established, since those lesions tend to exhibit lymph node ...
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Article
The efficacy of topical bupivacaine and triamcinolone acetonide injection in the relief of pain after endoscopic submucosal dissection for gastric neoplasia: a randomized double-blind, placebo-controlled trial
Although pain is a common complication of endoscopic submucosal dissection (ESD), management strategies are inadequate. The aim of this study was to evaluate the efficacy of topical bupivacaine and triamcinolo...
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Article
What are the risk factors for residual tumor cells after endoscopic complete resection in gastric epithelial neoplasia?
In early gastric cancer (EGC) and gastric adenoma, residual tumors may develop despite complete endoscopic resection (ER). To improve the chance of curative resection, we investigated the risk factors of resid...
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Article
Endoscopic Quality Indicators for Esophagogastroduodenoscopy in Gastric Cancer Screening
Quality indicators of screening esophagogastroduodenoscopy are essential to improve the detection rate of gastric cancer. However, a reliable, practical indicator of the performance of endoscopists in screenin...