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Article

Bisulfite-free epigenomics and genomics of single cells through methylation-sensitive restriction

Single-cell multi-omics are powerful means to study cell-to-cell heterogeneity. Here, we present a single-tube, bisulfite-free method for the simultaneous, genome-wide analysis of DNA methylation and genetic v...

Christoph Niemöller, Julius Wehrle, Julian Riba, Rainer Claus… in Communications Biology (2021)