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Article
Open AccessCurbing gastrointestinal infections by defensin fragment modifications without harming commensal microbiota
The occurrence and spread of multidrug-resistant pathogens, especially bacteria from the ESKAPE panel, increases the risk to succumb to untreatable infections. We developed a novel antimicrobial peptide, Pam-3...
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Article
Open AccessProteolytic Degradation of reduced Human Beta Defensin 1 generates a Novel Antibiotic Octapeptide
Microbial resistance against clinical used antibiotics is on the rise. Accordingly, there is a high demand for new innovative antimicrobial strategies. The host-defense peptide human beta-defensin 1 (hBD-1) is...
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Article
Netzbildung als Abwehrstrategie des menschlichen Körpers
The human organism is protected against commensal and pathogenic microbes by antimicrobial molecules of the innate immune system. The human beta defensin 1 (hBD1) is one of the most prominent antimicrobial mol...
