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  1. Article

    Open Access

    The meiotic TERB1-TERB2-MAJIN complex tethers telomeres to the nuclear envelope

    During meiotic prophase I, telomeres attach to and move on the nuclear envelope (NE), regulating chromosome movement to promote homologous pairing. Meiosis-specific proteins TERB1, TERB2 and MAJIN play a key r...

    Yan Wang, Yanyan Chen, Juan Chen, Lijun Wang, Leitong Nie… in Nature Communications (2019)

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  2. No Access

    Article

    Telomeric TERB1–TRF1 interaction is crucial for male meiosis

    Disrupting the interaction between telomere protein TRF1 with meiosis-specific protein TERB1 impairs the pairing of X and Y chromosomes via their telomere-adjacent pseudoautosomal regions in pachytene, leading...

    Juanjuan Long, Chenhui Huang, Yanyan Chen… in Nature Structural & Molecular Biology (2017)

  3. Article

    Structural and functional analyses of the mammalian TIN2-TPP1-TRF2 telomeric complex

    Telomeres are nucleoprotein complexes that play essential roles in protecting chromosome ends. Mammalian telomeres consist of repetitive DNA sequences bound by the shelterin complex. In this complex, the POT1-...

    Chunyi Hu, Rekha Rai, Chenhui Huang, Cayla Broton, Juanjuan Long, Ying Xu… in Cell Research (2017)

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