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Article
MiRNA-122-5p inhibitor abolishes angiotensin II–mediated loss of autophagy and promotion of apoptosis in rat cardiofibroblasts by modulation of the apelin-AMPK-mTOR signaling
MicroRNAs (miRNAs) have emerged as essential regulators that could have pivotal roles in cardiac homeostasis and pathological remodeling of various cardiovascular diseases. We previously demonstrated that miRN...
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Article
Hollow porous nanocuboids cobalt-based metal–organic frameworks with coordination defects as anode for enhanced lithium storage
Controlling the morphology of metal–organic frameworks to improve their application in energy storage remains a particular challenge. In this work, hollow porous Co-MOF-74 nanocuboids consisting of nanothorn (...
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Article
Elabela prevents angiotensin II-induced apoptosis and inflammation in rat aortic adventitial fibroblasts via the activation of FGF21–ACE2 signaling
Apoptosis, inflammation, and fibrosis contribute to vascular remodeling and injury. Elabela (ELA) serves as a crucial regulator to maintain vascular function and has been implicated in the pathogenesis of hype...
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Article
The Elabela-APJ axis: a promising therapeutic target for heart failure
Heart failure (HF) is a growing epidemic with high morbidity and mortality at an international scale. The apelin–APJ receptor pathway has been implicated in HF, making it a promising therapeutic target. APJ ha...
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Article
Gender Differences in Hypertension
Hypertension is the leading risk factor for global mortality and morbidity and remains the major preventable cause of cardiovascular diseases. Gender differences in risk factors and awareness, treatment, and c...
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Article
Isolation and Characterization of Three MADS-box Genes from Alpinia hainanensis (Zingiberaceae)
Three complementary DNA clones, AhMADS5, AhMADS6, and AhMADS8 were isolated from the young inflorescences of Alpinia hainanensis. Sequence comparisons and phylogenetic analyses indicated that AhMADS5 and AhMADS8 ...
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Article
Characteristics of the dynamic distribution of suspended particles in the flocculation process
Polyaluminium chloride (PAC) synthetic water was selected as a coagulant and kaolin suspension particles as objects to be removed. Online instruments such as the turbidimeter and particle counter were employed...