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  1. No Access

    Article

    Autoimmune diseases: targets, biology, and drug discovery

    Autoimmune diseases (AIDs) arise from a breakdown in immunological self-tolerance, wherein the adaptive immune system mistakenly attacks healthy cells, tissues and organs. AIDs impose excessive treatment costs...

    Shu-jie Li, Yan-li Wu, Juan-hua Chen, Shi-yi Shen, Jia Duan… in Acta Pharmacologica Sinica (2024)

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    Article

    Regulation of Calvin–Benson cycle enzymes under high temperature stress

    The Calvin–Benson cycle (CBC) consists of three critical processes, including fixation of CO2 by Rubisco, reduction of 3-phosphoglycerate (3PGA) to triose phosphate (triose-P) with NADPH and ATP generated by the ...

    Juan-Hua Chen, Ming Tang, Xue-Qi **, Han Li, Li-Sha Chen, Qing-Long Wang… in aBIOTECH (2022)

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    Article

    Nuclear-encoded synthesis of the D1 subunit of photosystem II increases photosynthetic efficiency and crop yield

    In photosynthetic organisms, the photosystem II (PSII) complex is the primary target of thermal damage. Plants have evolved a repair process to prevent the accumulation of damaged PSII. The repair of PSII larg...

    Juan-Hua Chen, Si-Ting Chen, Ning-Yu He, Qing-Long Wang, Yao Zhao, Wei Gao… in Nature Plants (2020)