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  1. Article

    Open Access

    PA-MSHA induces inflamed tumor microenvironment and sensitizes tumor to anti-PD-1 therapy

    A low response rate to immune checkpoint inhibitor (ICI) therapy has impeded its clinical use. As reported previously, an inflamed tumor microenvironment (TME) was directly correlated with patients’ response t...

    Min Huang, Fang He, Dan Li, Ya-Jia **e, Ze-Bo Jiang, Ju-Min Huang in Cell Death & Disease (2022)

  2. Article

    Open Access

    Evodiamine suppresses non-small cell lung cancer by elevating CD8+ T cells and downregulating the MUC1-C/PD-L1 axis

    Accumulating evidence showed that regulating tumor microenvironment plays a vital role in improving antitumor efficiency. Programmed Death Ligand 1 (PD-L1) is expressed in many cancer cell types, while its bin...

    Ze-Bo Jiang, Ju-Min Huang, Ya-Jia **e in Journal of Experimental & Clinical Cancer … (2020)