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Article
Open AccessTh2-biased immune responses to body migrating Ascaris larvae in primary infection are associated with pathology but not protection
Helminth infections lead to an overdispersion of the parasites in humans as well as in animals. We asked whether early immune responses against migrating Ascaris larvae are responsible for the unequal distributio...
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Article
Open AccessAcute Ascaris infection impairs the effector functions of natural killer cells in single and Salmonella co-infected pigs
Natural killer (NK) cells play a key role in defense against Salmonella infections during the early phase of infection. Our previous work showed that the excretory/secretory products of Ascaris suum repressed NK ...
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Article
Open AccessPersistent Plasmodium falciparum infections enhance transmission-reducing immunity development
Subclinical infections that serve as reservoir populations to drive transmission remain a hurdle to malaria control. Data on infection dynamics in a geographical area is required to strategically design and im...
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Article
Open AccessSeasonal variations in Plasmodium falciparum genetic diversity and multiplicity of infection in asymptomatic children living in southern Ghana
Genetic diversity in Plasmodium falciparum (P. falciparum) parasites is a major hurdle to the control of malaria. This study monitored changes in the genetic diversity and the multiplicity of P. falciparum parasi...
