-
Article
Open AccessRubella virus genotype 2B endemicity and related utility of serum-based molecular characterization in Uganda
There are 13 globally recognized rubella virus genotypes of which only 2 (1E and 2B) have been detected recently. The largest percentage of all reported rubella virus sequences come from China and Japan with A...
-
Article
Open AccessSabin polio virus protein 1 (VP1) evolution in patients with acute flaccid paralysis from 2010 to 2016 in Uganda
Acute flaccid paralysis (AFP) is a rare side effect of the oral polio vaccine but can be associated with outbreaks and permanent disability in patients harboring circulating vaccine-derived polioviruses (cVDPV...
-
Article
Open AccessInvestigating the etiology of acute febrile illness: a prospective clinic-based study in Uganda
Historically, malaria has been the predominant cause of acute febrile illness (AFI) in sub-Saharan Africa. However, during the last two decades, malaria incidence has declined due to concerted public health co...
-
Article
Open AccessEnvironmental surveillance detects circulating vaccine-derived poliovirus type 2 that was undetected by acute flaccid paralysis surveillance in 2021 in Uganda
The success of the global polio eradication initiative is threatened by the genetic instability of the oral polio vaccine, which can result in the emergence of pathogenic vaccine-derived polioviruses following...
-
Article
Open AccessUganda’s experience in Ebola virus disease outbreak preparedness, 2018–2019
Since the declaration of the 10th Ebola Virus Disease (EVD) outbreak in DRC on 1st Aug 2018, several neighboring countries have been develo** and implementing preparedness efforts to prevent EVD cross-border...
-
Article
Open AccessThe detection of 3 ambiguous type 2 vaccine-derived polioviruses (VDPV2s) in Uganda
The Oral Polio Vaccine (OPV or Sabin) is genetically unstable and may mutate to form vaccine-derived polioviruses (VDPVs).
-
Article
Open AccessThe epidemiology of rotavirus disease in under-five-year-old children hospitalized with acute diarrhea in central Uganda, 2012-2013
A cross-sectional study was undertaken during 2012-2013 to determine the prevalence, strains and factors associated with rotavirus infection among under-5-year-old children hospitalized with acute diarrhea in ...
-
Article
Open AccessPrevalence of influenza A viruses in livestock and free-living waterfowl in Uganda
Avian influenza viruses may cause severe disease in a variety of domestic animal species worldwide, with high mortality in chickens and turkeys. To reduce the information gap about prevalence of these viruses ...
-
Article
Open AccessGenetic analysis of influenza B viruses isolated in Uganda during the 2009–2010 seasons
Influenza B viruses can cause morbidity and mortality in humans but due to the lack of an animal reservoir are not associated with pandemics. Because of this, there is relatively limited genetic sequences avai...
-
Article
Open AccessSero-prevalence and risk factors for hepatitis B virus infection among health care workers in a tertiary hospital in Uganda
Hepatitis B virus (HBV) infection is a global public health challenge. Prevalence of current hepatitis B virus infection in the general population in Uganda is about 10%. Health care workers (HCW) have an extr...
