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  1. No Access

    Article

    DNA.Land is a framework to collect genomes and phenomes in the era of abundant genetic information

    Creating large genome/phenome collections can require consortium-scale resources. DNA.Land is a digital biobank that collects genetic data from individuals tested by consumer genomic companies using a fraction...

    Jie Yuan, Assaf Gordon, Daniel Speyer, Richard Aufrichtig… in Nature Genetics (2018)

  2. No Access

    Article

    Genome-wide patterns of selection in 230 ancient Eurasians

    Ancient DNA makes it possible to observe natural selection directly by analysing samples from populations before, during and after adaptation events. Here we report a genome-wide scan for selection using ancie...

    Iain Mathieson, Iosif Lazaridis, Nadin Rohland, Swapan Mallick, Nick Patterson… in Nature (2015)

  3. No Access

    Article

    The complete genome sequence of a Neanderthal from the Altai Mountains

    We present a high-quality genome sequence of a Neanderthal woman from Siberia. We show that her parents were related at the level of half-siblings and that mating among close relatives was common among her rec...

    Kay Prüfer, Fernando Racimo, Nick Patterson, Flora Jay, Sriram Sankararaman… in Nature (2014)

  4. Article

    Open Access

    A mixture model approach to multiple testing for the genetic analysis of gene expression

    With the availability of very dense genome-wide maps of markers, multiple testing has become a major difficulty for genetic studies. In this context, the false-discovery rate (FDR) and related criteria are wid...

    Cyril Dalmasso, Joseph Pickrell, Marianne Tuefferd, Emmanuelle Génin… in BMC Proceedings (2007)

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