4 Result(s)
within
Joseph Borg
Science, Humanities and Social Sciences, multidisciplinary
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Article
Open AccessEthical considerations for the age of non-governmental space exploration
Mounting ambitions and capabilities for public and private, non-government sector crewed space exploration bring with them an increasingly diverse set of space travelers, raising new and nontrivial ethical, le...
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Article
Open AccessSpatiotemporal expression and control of haemoglobin in space
It is now widely recognised that the environment in space activates a diverse set of genes involved in regulating fundamental cellular pathways. This includes the activation of genes associated with blood home...
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Article
Open AccessEpigenomic analysis of KLF1 haploinsufficiency in primary human erythroblasts
Haploinsufficiency for the erythroid-specific transcription factor KLF1 is associated with hereditary persistence of fetal hemoglobin (HPFH). Increased HbF ameliorates the symptoms of β-hemoglobinopathies and ...
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Article
Open AccessAspirin impairs acetyl-coenzyme A metabolism in redox-compromised yeast cells
Aspirin is a widely used anti-inflammatory and antithrombotic drug also known in recent years for its promising chemopreventive antineoplastic properties, thought to be mediated in part by its ability to induc...
