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Article
Open AccessInfluence of variability in the cyclooxygenase pathway on cardiovascular outcomes of nephrosclerosis patients
Nephrosclerosis patients are at an exceptionally high cardiovascular (CV) risk. We aimed to determine whether genetic variability represented by 38 tag-SNPs in genes of the cyclooxygenase pathway (PTGS1, PTGS2, P...
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Article
Correction to: Hyperkalemia in Chronic Kidney Disease in the New Era of Kidney Protection Therapies
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Article
Hyperkalemia in Chronic Kidney Disease in the New Era of Kidney Protection Therapies
Despite recent therapeutic advances, chronic kidney disease (CKD) is one of the fastest growing global causes of death. This illustrates limitations of current therapeutic approaches and, potentially, unidenti...
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Functional Distribution and Regulation of the NMDAR in the Kidney, Heart and Parathyroid Gland
N-Methyl-d-aspartate receptor (NMDAR) is an ionotropic glutamate receptor with a high permeability to calcium and a unique feature of controlling numerous calcium-dependent processes. Apart of being widely distr...
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Article
Open AccessA low fractional excretion of Phosphate/Fgf23 ratio is associated with severe abdominal Aortic calcification in stage 3 and 4 kidney disease patients
Vascular calcification (VC) contributes to high mortality rates in chronic kidney disease (CKD). High serum phosphate and FGF23 levels and impaired phosphaturic response to FGF23 may affect VC. Therefore, thei...
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Inhibition of 5-lo Activating Protein (Flap) Activity Decreases Proteinuria in Streptozotocin(Stz)-induced Diabetic Rats.
Proteinuria is a major cause of morbidity in patients with glomerular disease. Nonselective protein filtration is now recognized as a significant contributing factor to the tubulo-interstitial injury which und...
