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Article
Early stages of diffuse idiopathic skeletal hyperostosis (DISH) and chronic inflammation: the Camargo Cohort Study
DISH has traditionally been considered a non-inflammatory rheumatic disorder. Currently, an inflammatory component has been theorized in the early phases of this condition (EDISH). The study is aimed at invest...
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Article
Open AccessResponse of a high-speed train travelling over a long and high-pier viaduct during moderate earthquakes
This contribution presents the results of numerical simulations in which a high-pier viaduct under lateral and vertical non-stationary spatially variable seismic ground motions is crossed by an articulated hig...
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Article
Open AccessSarcopenic osteoporosis, sarcopenic obesity, and sarcopenic osteoporotic obesity in the Camargo cohort (Cantabria, Spain)
The associations of sarcopenia with osteoporosis or obesity have a very low prevalence. No trend towards an association between osteoporosis and sarcopenia is observed. Sarcopenia and obesity tend not to coinc...
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Article
Bone mineral density and trabecular bone score in treatment-naïve patients with non-cirrhotic hepatitis C virus infection
We studied 112 treatment-naïve chronic HCV patients without cirrhosis, and we found that, especially HCV+ postmenopausal women, they had lower TBS and BMD values than healthy controls. This suggests that HCV i...
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Article
Serum 25-Hydroxyvitamin D in Obese Spanish Adults: the Camargo Cohort Study
To describe the 25(OH)D status in Spanish obese postmenopausal women and men ≥ 50 years, to compare their results with those of the overweight or normal weight population, and to determine whether differences ...
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Article
Prevalence of vertebral fracture and densitometric osteoporosis in Spanish adult men: The Camargo Cohort Study
The aim of this study was to assess the prevalence of densitometric osteoporosis and vertebral fractures in Spanish men aged ≥50 years, and to study how the relationship between them may change depending on ho...
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Article
Open AccessIncretins in patients with rheumatoid arthritis
The precise mechanism linking systemic inflammation with insulin resistance (IR) in rheumatoid arthritis (RA) remains elusive. In the present study, we determined whether the incretin-insulin axis and incretin...
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Article
Open AccessHDL cholesterol efflux capacity in rheumatoid arthritis patients: contributing factors and relationship with subclinical atherosclerosis
Lipid profiles appear to be altered in rheumatoid arthritis (RA) patients because of disease activity and inflammation. Cholesterol efflux capacity (CEC), which is the ability of high-density lipoprotein chole...
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Article
Open AccessSNPs in bone-related miRNAs are associated with the osteoporotic phenotype
Biogenesis and function of microRNAs can be influenced by genetic variants in the pri-miRNA sequences leading to phenotypic variability. This study aims to identify single nucleotide polymorphisms (SNPs) affec...
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Article
Relationship between spinal osteoarthritis and vertebral fractures in men older than 50 years: data from the Camargo Cohort Study
Spinal osteoarthritis has been suggested as a risk factor for vertebral fractures. However, results are conflicting: most of the data are focused on the lumbar region, and referred to postmenopausal women, whe...
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Article
Exon array analysis reveals genetic heterogeneity in atypical femoral fractures. A pilot study
Atraumatic subtrochanteric and diaphyseal (atypical) femoral fractures are a rare, but important adverse event in patients treated with potent anti-resortive agents. The mechanisms involved are unknown and par...
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Article
Bone mineral density in statin users: a population-based analysis from a Spanish cohort
We studied 2,315 subjects (1,422 women and 893 men) from the Camargo Cohort and analyzed the differences in BMD between statin or non-statin users. We also studied effects of the type of statin, dose, pharmaco...
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Article
Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture
Fernando Rivadeneira and colleagues in the Genetic Factors for Osteoporosis Consortium report a large-scale meta-analysis identifying new loci associated with bone mineral density (BMD) and risk of fracture. T...
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Article
Mineral Metabolism in Obese Patients Following Vertical Banded Gastroplasty
Bone disease has been described in patients after surgical treatment for obesity, but few studies have dealt with the impact of vertical banded gastroplasty on mineral metabolism. We have examined bone mineral...
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Article
Trend in hip fracture epidemiology over a 14-year period in a Spanish population
Spain lacks detailed data on hip fracture trends despite being the country with the greatest increase in the pensioner-to-provider ratio in Europe. We reproduced a study on hip fracture incidence in a region o...
