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Article
Open AccessA Data Augmentation Methodology to Reduce the Class Imbalance in Histopathology Images
Deep learning techniques have recently yielded remarkable results across various fields. However, the quality of these results depends heavily on the quality and quantity of data used during the training phase...
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Article
Open AccessMMIR: an open-source software for the registration of multimodal histological images
Multimodal histology image registration is a process that transforms into a common coordinate system two or more images obtained from different microscopy modalities. The combination of information from variou...
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Chapter and Conference Paper
Optimizing Variant Calling for Human Genome Analysis: A Comprehensive Pipeline Approach
The identification of genetic variations in large cohorts is a critical issue to identify patient cohorts, disease risks, and to develop more effective treatments. To help this analysis, we improved a variant ...
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Article
Normalizing Heterogeneous Medical Imaging Data to Measure the Impact of Radiation Dose
The production of medical imaging is a continuing trend in healthcare institutions. Quality assurance for planned radiation exposure situations (e.g. X-ray, computer tomography) requires examination-specific s...
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Article
Sensor-Based Architecture for Medical Imaging Workflow Analysis
The growing use of computer systems in medical institutions has been generating a tremendous quantity of data. While these data have a critical role in assisting physicians in the clinical practice, the inform...
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Article
Open AccessgeneCommittee: a web-based tool for extensively testing the discriminatory power of biologically relevant gene sets in microarray data classification
The diagnosis and prognosis of several diseases can be shortened through the use of different large-scale genome experiments. In this context, microarrays can generate expression data for a huge set of genes. ...
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Article
DICOM relay over the cloud
Healthcare institutions worldwide have adopted picture archiving and communication system (PACS) for enterprise access to images, relying on Digital Imaging Communication in Medicine (DICOM) standards for data...
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Article
A PACS archive architecture supported on cloud services
Diagnostic imaging procedures have continuously increased over the last decade and this trend may continue in coming years, creating a great impact on storage and retrieval capabilities of current PACS. Moreov...
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Chapter and Conference Paper
Prioritizing Literature Search Results Using a Training Set of Classified Documents
Finding relevant articles is rapidly becoming a demanding task for researchers in the biomedical field, due to the rapid expansion of the scientific literature. We investigate the use of ranking strategies for...
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Article
Open AccessConcept-based query expansion for retrieving gene related publications from MEDLINE
Advances in biotechnology and in high-throughput methods for gene analysis have contributed to an exponential increase in the number of scientific publications in these fields of study. While much of the data ...
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Chapter and Conference Paper
Improving Cross Map** in Biomedical Databases
The complete analysis of many large scale experiments requires the comparison of the produced output with data available in public databases. Because each datapbase uses its own nomenclature to classify entrie...
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Chapter and Conference Paper
Expanding Gene-Based PubMed Queries
The rapid expansion of the scientific literature is turning the task of finding relevant articles into a demanding one for researchers working in the biomedical field. We investigate the use of a query expansi...
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Chapter and Conference Paper
An Application for Studying Tandem Repeats in Orthologous Genes
Several authors have being suggesting that the occurrence of amino acids repeats in some genes are implied in human diseases. We aim to investigate if these repetitions, which one can observe in humans, also e...
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Chapter and Conference Paper
Syntactic Parsing for Bio-molecular Event Detection from Scientific Literature
Rapid advances in science and in laboratorial and computing methods are generating vast amounts of data and scientific literature. In order to keep up-to-date with the expanding knowledge in their field of stu...
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Chapter and Conference Paper
Analysing the Evolution of Repetitive Strands in Genomes
The analysis of genomes and proteomes of the various organisms allow us to observe its behaviour in the evolution of species. In this study, we focus our attention on a particular aspect of this analysis: the ...
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Chapter and Conference Paper
Improving Literature Searches in Gene Expression Studies
MEDLINE is the premier literature database in the biomedical and life sciences fields, containing over 17 million references to journal articles. Searching in this database can be performed through PubMed, a w...
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Chapter and Conference Paper
A Prospective Study on the Integration of Microarray Data in HIS/EPR
The successful completion of the Human Genome Project promised an increase on our knowledge about the way our organism works and therefore would have a major impact in medicine. DNA microarray is one of the te...
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Chapter and Conference Paper
Active Traffic Monitoring for Heterogeneous Environments
The traffic management of IP networks faces increasing challenges, due to the occurrence of sudden and deep traffic variations in the network, which can be mainly attributed to the large diversity of supported...
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Chapter and Conference Paper
A Mobile Agent Manager
Friendliness on user interfaces has been mostly forgot in mobile agent research. In fact the multitude of problems that have to be solved have left this more “simple” piece of the package out of target. Howeve...
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Chapter and Conference Paper
Multi-management Schemes for MAF Platforms
Due to the crescent complexity of networks and systems, network management solutions are being pushed towards more distributed and cooperative models. Several specifications promoted by the IETF DISMAN charter...