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  1. Article

    Open Access

    A Data Augmentation Methodology to Reduce the Class Imbalance in Histopathology Images

    Deep learning techniques have recently yielded remarkable results across various fields. However, the quality of these results depends heavily on the quality and quantity of data used during the training phase...

    Rodrigo Escobar Díaz Guerrero, Lina Carvalho in Journal of Imaging Informatics in Medicine (2024)

  2. Article

    Open Access

    MMIR: an open-source software for the registration of multimodal histological images

    Multimodal histology image registration is a process that transforms into a common coordinate system two or more images obtained from different microscopy modalities. The combination of information from variou...

    Rodrigo Escobar Díaz Guerrero in BMC Medical Informatics and Decision Making (2024)

  3. No Access

    Chapter and Conference Paper

    Optimizing Variant Calling for Human Genome Analysis: A Comprehensive Pipeline Approach

    The identification of genetic variations in large cohorts is a critical issue to identify patient cohorts, disease risks, and to develop more effective treatments. To help this analysis, we improved a variant ...

    Miguel Pinheiro, Jorge Miguel Silva in Bioinformatics and Biomedical Engineering (2023)

  4. No Access

    Article

    Normalizing Heterogeneous Medical Imaging Data to Measure the Impact of Radiation Dose

    The production of medical imaging is a continuing trend in healthcare institutions. Quality assurance for planned radiation exposure situations (e.g. X-ray, computer tomography) requires examination-specific s...

    Luís A. Bastião Silva, Luís S. Ribeiro, Milton Santos in Journal of Digital Imaging (2015)

  5. No Access

    Article

    Sensor-Based Architecture for Medical Imaging Workflow Analysis

    The growing use of computer systems in medical institutions has been generating a tremendous quantity of data. While these data have a critical role in assisting physicians in the clinical practice, the inform...

    Luís A. Bastião Silva, Samuel Campos, Carlos Costa in Journal of Medical Systems (2014)

  6. Article

    Open Access

    geneCommittee: a web-based tool for extensively testing the discriminatory power of biologically relevant gene sets in microarray data classification

    The diagnosis and prognosis of several diseases can be shortened through the use of different large-scale genome experiments. In this context, microarrays can generate expression data for a huge set of genes. ...

    Miguel Reboiro-Jato, Joel P Arrais, José Luis Oliveira in BMC Bioinformatics (2014)

  7. No Access

    Article

    DICOM relay over the cloud

    Healthcare institutions worldwide have adopted picture archiving and communication system (PACS) for enterprise access to images, relying on Digital Imaging Communication in Medicine (DICOM) standards for data...

    Luís A. Bastião Silva, Carlos Costa in International Journal of Computer Assisted… (2013)

  8. No Access

    Article

    A PACS archive architecture supported on cloud services

    Diagnostic imaging procedures have continuously increased over the last decade and this trend may continue in coming years, creating a great impact on storage and retrieval capabilities of current PACS. Moreov...

    Luís A. Bastião Silva, Carlos Costa in International Journal of Computer Assisted… (2012)

  9. No Access

    Chapter and Conference Paper

    Prioritizing Literature Search Results Using a Training Set of Classified Documents

    Finding relevant articles is rapidly becoming a demanding task for researchers in the biomedical field, due to the rapid expansion of the scientific literature. We investigate the use of ranking strategies for...

    Sérgio Matos, José Luis Oliveira in 5th International Conference on Practical … (2011)

  10. Article

    Open Access

    Concept-based query expansion for retrieving gene related publications from MEDLINE

    Advances in biotechnology and in high-throughput methods for gene analysis have contributed to an exponential increase in the number of scientific publications in these fields of study. While much of the data ...

    Sérgio Matos, Joel P Arrais, João Maia-Rodrigues, José Luis Oliveira in BMC Bioinformatics (2010)

  11. No Access

    Chapter and Conference Paper

    Improving Cross Map** in Biomedical Databases

    The complete analysis of many large scale experiments requires the comparison of the produced output with data available in public databases. Because each datapbase uses its own nomenclature to classify entrie...

    Joel Arrais, João E. Pereira, Pedro Lopes, Sérgio Matos in Advances in Bioinformatics (2010)

  12. No Access

    Chapter and Conference Paper

    Expanding Gene-Based PubMed Queries

    The rapid expansion of the scientific literature is turning the task of finding relevant articles into a demanding one for researchers working in the biomedical field. We investigate the use of a query expansi...

    Sérgio Matos, Joel P. Arrais, José Luis Oliveira in Advances in Bioinformatics (2010)

  13. No Access

    Chapter and Conference Paper

    An Application for Studying Tandem Repeats in Orthologous Genes

    Several authors have being suggesting that the occurrence of amino acids repeats in some genes are implied in human diseases. We aim to investigate if these repetitions, which one can observe in humans, also e...

    José Paulo Lousado, José Luis Oliveira, Gabriela Moura in Advances in Bioinformatics (2010)

  14. No Access

    Chapter and Conference Paper

    Syntactic Parsing for Bio-molecular Event Detection from Scientific Literature

    Rapid advances in science and in laboratorial and computing methods are generating vast amounts of data and scientific literature. In order to keep up-to-date with the expanding knowledge in their field of stu...

    Sérgio Matos, Anabela Barreiro, José Luis Oliveira in Progress in Artificial Intelligence (2009)

  15. No Access

    Chapter and Conference Paper

    Analysing the Evolution of Repetitive Strands in Genomes

    The analysis of genomes and proteomes of the various organisms allow us to observe its behaviour in the evolution of species. In this study, we focus our attention on a particular aspect of this analysis: the ...

    José P. Lousado, José Luis Oliveira in Distributed Computing, Artificial Intellig… (2009)

  16. No Access

    Chapter and Conference Paper

    Improving Literature Searches in Gene Expression Studies

    MEDLINE is the premier literature database in the biomedical and life sciences fields, containing over 17 million references to journal articles. Searching in this database can be performed through PubMed, a w...

    Joel P. Arrais, João G. L. M. Rodrigues in 2nd International Workshop on Practical Ap… (2009)

  17. No Access

    Chapter and Conference Paper

    A Prospective Study on the Integration of Microarray Data in HIS/EPR

    The successful completion of the Human Genome Project promised an increase on our knowledge about the way our organism works and therefore would have a major impact in medicine. DNA microarray is one of the te...

    Daniel F. Polónia, Joel Arrais, José Luis Oliveira in Biological and Medical Data Analysis (2006)

  18. No Access

    Chapter and Conference Paper

    Active Traffic Monitoring for Heterogeneous Environments

    The traffic management of IP networks faces increasing challenges, due to the occurrence of sudden and deep traffic variations in the network, which can be mainly attributed to the large diversity of supported...

    Hélder Veiga, Teresa Pinho, José Luis Oliveira, Rui Valadas in Networking - ICN 2005 (2005)

  19. No Access

    Chapter and Conference Paper

    A Mobile Agent Manager

    Friendliness on user interfaces has been mostly forgot in mobile agent research. In fact the multitude of problems that have to be solved have left this more “simple” piece of the package out of target. Howeve...

    Rui Pedro Lopes, José Luis Oliveira in Mobile Agents for Telecommunication Applications (2003)

  20. No Access

    Chapter and Conference Paper

    Multi-management Schemes for MAF Platforms

    Due to the crescent complexity of networks and systems, network management solutions are being pushed towards more distributed and cooperative models. Several specifications promoted by the IETF DISMAN charter...

    Rui Pedro Lopes, José Luis Oliveira in Mobile Agents for Telecommunication Applications (2002)

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