Skip to main content

3 Result(s)

within Behavioral Sciences Remove this filter Medicine/Public Health, general Remove this filter Neurosciences Remove this filter Jorge Urresti Remove this filter

and

  1. Article

    Open Access

    Autism-linked Cullin3 germline haploinsufficiency impacts cytoskeletal dynamics and cortical neurogenesis through RhoA signaling

    E3-ubiquitin ligase Cullin3 (Cul3) is a high confidence risk gene for autism spectrum disorder (ASD) and developmental delay (DD). To investigate how Cul3 mutations impact brain development, we generated a haploi...

    Megha Amar, Akula Bala Pramod, Nam-Kyung Yu, Victor Munive Herrera… in Molecular Psychiatry (2021)

    Download PDF (7959 KB) View Article

  2. Article

    Correction: Cortical organoids model early brain development disrupted by 16p11.2 copy number variants in autism

    Jorge Urresti, Pan Zhang, Patricia Moran-Losada, Nam-Kyung Yu… in Molecular Psychiatry (2021)

    Download PDF (295 KB) View Article

  3. Article

    Open Access

    Cortical organoids model early brain development disrupted by 16p11.2 copy number variants in autism

    Reciprocal deletion and duplication of the 16p11.2 region is the most common copy number variation (CNV) associated with autism spectrum disorders. We generated cortical organoids from skin fibroblasts of pati...

    Jorge Urresti, Pan Zhang, Patricia Moran-Losada, Nam-Kyung Yu… in Molecular Psychiatry (2021)

    Download PDF (4629 KB) View Article