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Article
Predominance of visuoconstructive impairment after mild COVID-19?
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Article
Open AccessGA-MADRID: design and validation of a machine learning tool for the diagnosis of Alzheimer’s disease and frontotemporal dementia using genetic algorithms
Artificial Intelligence aids early diagnosis and development of new treatments, which is key to slow down the progress of the diseases, which to date have no cure. The patients’ evaluation is carried out throu...
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Article
Inhibition impairment in frontotemporal dementia, amyotrophic lateral sclerosis, and Alzheimer’s disease: clinical assessment and metabolic correlates
The ability to reject an automatic tendency, i.e. inhibition, has been linked to the prefrontal cortex, but its neural underpinnings are still controversial. Neurodegenerative diseases represent an interesting...
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Article
Open AccessStructural MRI correlates of PASAT performance in multiple sclerosis
The Paced Auditory Serial Addition Test (PASAT) is a useful cognitive test in patients with multiple sclerosis (MS), assessing sustained attention and information processing speed. However, the neural underpin...
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Article
Open AccessAmyotrophic lateral sclerosis modifies progenitor neural proliferation in adult classic neurogenic brain niches
Adult neurogenesis persists through life at least in classic neurogenic niches. Neurogenesis has been previously described as reduced in neurodegenerative diseases. There is not much knowledge about is adult n...
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Article
Amyloid- and FDG-PET imaging in amyotrophic lateral sclerosis
We aimed to study brain metabolism and presence of beta-amyloid deposits using positron emission tomography (PET) in patients with amyotrophic lateral sclerosis (ALS).
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Article
Open AccessAmyloid PET imaging in multiple sclerosis: an 18F-florbetaben study
Positron emission tomography (PET) images with amyloid tracers show normal uptake in healthy white matter, which suggests that amyloid tracers are potentially useful for studying such white matter diseases as ...
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Article
Amyloid and FDG-PET study of logopenic primary progressive aphasia: evidence for the existence of two subtypes
The logopenic variant of primary progressive aphasia (lvPPA) has been associated with Alzheimer disease, although this relationship is still subject to debate. The purpose of this study is to determine the fre...
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Article
Visual and statistical analysis of 18F-FDG PET in primary progressive aphasia
Diagnosing progressive primary aphasia (PPA) and its variants is of great clinical importance, and fluorodeoxyglucose (FDG) positron emission tomography (PET) may be a useful diagnostic technique. The purpose ...
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Article
Clinical course of primary progressive aphasia: clinical and FDG-PET patterns
Primary progressive aphasia (PPA) may be the onset of several neurodegenerative diseases. This study evaluates a cohort of patients with PPA to assess their progression to different clinical syndromes, associa...
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Article
Open AccessParoxysmal head pain with backward radiation: will epicrania fugax go in the opposite direction?
Epicrania fugax (EF) has been recently described as a paroxysmal head pain starting in a focal cranial area of the posterior scalp and rapidly spreading forward to the ipsilateral eye or nose along a linear or...
