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    Generation of a Proteolytic Signal: E3/E2-Mediated Polyubiquitination of IκBα

    A key regulatory node in NF-κB signaling is the removal of the IκBα inhibitor, whose levels are tightly controlled by the ubiquitin–proteasome system. In response to signal activation and transmission, ubiquit...

    Robert A. Chong, Kenneth Wu, Jordan Kovacev, Zhen-Qiang Pan in NF-kappa B (2015)