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Article
Open AccessReliability of brain atrophy measurements in multiple sclerosis using MRI: an assessment of six freely available software packages for cross-sectional analyses
Volume measurement using MRI is important to assess brain atrophy in multiple sclerosis (MS). However, differences between scanners, acquisition protocols, and analysis software introduce unwanted variability ...
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Article
Open AccessASL-BIDS, the brain imaging data structure extension for arterial spin labeling
Arterial spin labeling (ASL) is a non-invasive MRI technique that allows for quantitative measurement of cerebral perfusion. Incomplete or inaccurate reporting of acquisition parameters complicates quantificat...
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Article
Open AccessStrain analysis in CRT candidates using the novel segment length in cine (SLICE) post-processing technique on standard CMR cine images
Although myocardial strain analysis is a potential tool to improve patient selection for cardiac resynchronization therapy (CRT), there is currently no validated clinical approach to derive segmental strains. ...
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Article
Open AccessLower cerebral blood flow is associated with faster cognitive decline in Alzheimer’s disease
To determine whether lower cerebral blood flow (CBF) is associated with faster cognitive decline in patients with Alzheimer’s disease (AD).
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Article
Open AccessCerebral perfusion in the predementia stages of Alzheimer’s disease
To investigate arterial spin-labelling (ASL) cerebral blood flow (CBF) changes in predementia stages of Alzheimer’s disease (AD).
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Article
Reproducibility of pharmacological ASL using sequences from different vendors: implications for multicenter drug studies
The current study assesses the multicenter feasibility of pharmacological arterial spin labeling (ASL) by comparing a caffeine-induced relative cerebral blood flow decrease (%CBF↓) measured with two pseudo-co...
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Article
Open AccessCerebral perfusion and glucose metabolism in Alzheimer’s disease and frontotemporal dementia: two sides of the same coin?
Alzheimer’s disease (AD) and frontotemporal (FTD) dementia can be differentiated using [18F]-2-deoxy-2-fluoro-D-glucose (FDG)-PET. Since cerebral blood flow (CBF) is related to glucose metabolism, our aim was to ...
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Article
MRI T2* map** correlates with biochemistry and histology in intervertebral disc degeneration in a large animal model
To evaluate intervertebral disc (IVD) degeneration and treatments, an objective diagnostic tool is needed. Recently, T2* relaxation time map** was proposed as a technique to assess early IVD degeneration, ye...
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Article
Differentiation of edema and glioma infiltration: proposal of a DTI-based probability map
Conflicting results on differentiating edema and glioma by diffusion tensor imaging (DTI) are possibly attributable to dissimilar spatial distribution of the lesions. Combining DTI-parameters and enhanced regi...
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Article
Distinct perfusion patterns in Alzheimer’s disease, frontotemporal dementia and dementia with Lewy bodies
To compare pseudo-continuous arterial spin-labelled (PCASL) magnetic resonance imaging (MRI) measured quantitative cerebral blood flow (CBF) of patients with frontotemporal dementia (FTD), dementia with Lewy B...
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Article
Morphological features of MS lesions on FLAIR* at 7 T and their relation to patient characteristics
Recently, a new MRI technique was developed at 3 Tesla (T), called fluid attenuated inversion recovery* (FLAIR*). In this study, we implemented FLAIR* in an existing MS cohort at 7 T, to investigate whether we...
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Article
Improved differentiation between MS and vascular brain lesions using FLAIR* at 7 Tesla
To investigate whether a new magnetic resonance image (MRI) technique called T2*-weighted fluid attenuation inversion recovery (FLAIR*) can differentiate between multiple sclerosis (MS) and vascular brain lesi...
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Article
Impact of alcohol septal ablation on left anterior descending coronary artery blood flow in hypertrophic obstructive cardiomyopathy
Objectives The aim of this study was to evaluate the effects of alcohol septal ablation (ASA) on coronary blood flow in symptomatic hypertrophic obstructive cardiomyopathy (HOCM) using cardiac MR (CMR) coronary f...
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Article
Myocardial tagging with steady state free precession techniques and semi-automatic postprocessing—impact on diagnostic value
Our aim was to determine the diagnostic value of myocardial tagging sequences with regard to the evaluable share of the cardiac cycle. Thirty-three patients were examined at 1.5 T using tagging sequences with ...
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Article
Open AccessGlucocorticoids Decrease Hippocampal and Prefrontal Activation during Declarative Memory Retrieval in Young Men
Glucocorticoids (GCs, cortisol in human) are associated with impairments in declarative memory retrieval. Brain regions hypothesized to mediate these effects are the hippocampus and prefrontal cortex (PFC). Ou...
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Article
Regional heterogeneity of resting perfusion in hypertrophic cardiomyopathy is related to delayed contrast enhancement but not to systolic function: A PET and MRI study
Regional differences in resting myocardial blood flow (MBF) have been observed in patients with hypertrophic cardiomyopathy (HCM), but their determinants are currently unknown. This study verifies whether MBF ...
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Article
Variance components of two-dimensional strain parameters in the left-ventricular heart wall obtained by magnetic resonance tagging
This study quantifies variance components of two-dimensional strains in the left-ventricular heart wall assessed by magnetic resonance (MR) tagging in 18 healthy xxvolunteers. For a 7-mm tagging grid and homog...
