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Article
Association of IL23R polymorphism (rs7530511) with intracerebral hemorrhage in Korean population
Cytokines and their receptors are involved in the development of intracerebral hemorrhage (ICH). Interleukin 23 receptor (IL23R) has been implicated in numerous inflammatory and immune diseases. In this study,...
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Article
Association Between Paraoxonase Gene Polymorphisms and Intracerebral Hemorrhage in a Korean Population
The human paraoxonase (PON) gene family includes three members: PON1, PON2, and PON3. PON, which prevents the oxidative modification of lipoproteins, has been implicated as a potential risk factor of the cereb...
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Article
Protective Effect of Carbamazepine on Kainic Acid-induced Neuronal Cell Death Through Activation of Signal Transducer and Activator of Transcription-3
Studies have shown that the protective effect of carbamazepine (CBZ) on seizure-induced neuronal injury. However, its precise mechanisms remain unknown. Here, to investigate the neuroprotective mechanism of CB...
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Article
Association of Toll-like Receptor 2 Polymorphisms with National Institute of Health Stroke Scale Scores of Ischemic Stroke Patients
Toll-like receptor 2 (TLR2) has been shown to have an important role in the postischemic inflammatory response and to contribute to ischemic brain damage. In this study, we investigated whether coding region s...
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Article
Association of Polymorphism in the Promoter of the Melatonin Receptor 1A Gene with Schizophrenia and with Insomnia Symptoms in Schizophrenia Patients
Schizophrenia patients commonly have sleep disturbances. In this study, we investigated whether single nucleotide polymorphisms (SNPs) in the promoter region of the melatonin receptor genes (MTNR1A and MTNR1B)...
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Article
Open AccessAssociation between polymorphisms of arachidonate 12-lipoxygenase (ALOX12) and schizophrenia in a Korean population
Arachidonic acid (AA), an essential polyunsaturated fatty acid, is one of the major components of neural membranes, which show an altered phospholipid composition in schizophrenia. Arachidonate 12-lipoxygenase (A...
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Article
Open AccessAssociation study of polymorphisms in synaptic vesicle-associated genes, SYN2 and CPLX2, with schizophrenia
The occurrence of aberrant functional connectivity in the neuronal circuit is one of the integrative theories of the etiology of schizophrenia. Previous studies have reported that the protein and mRNA levels o...