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Article
Open AccessRNA-binding proteins and exoribonucleases modulating miRNA in cancer: the enemy within
Recent progress in the investigation of microRNA (miRNA) biogenesis and the miRNA processing machinery has revealed previously unknown roles of posttranscriptional regulation in gene expression. The molecular ...
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Article
Lipocalin-2 Is a Key Regulator of Neuroinflammation in Secondary Traumatic and Ischemic Brain Injury
Reactive glial cells are hallmarks of brain injury. However, whether these cells contribute to secondary inflammatory pathology and neurological deficits remains poorly understood. Lipocalin-2 (LCN2) has infla...
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Article
Ballistic Penetration Test and Simulation of Metallic Aircraft Wing Fuel Tank
The development of a fighter aircraft requires reasonable assessment and validation of airframe survivability against weapon threats. Fulfilling this objective and effectively meeting the combat survivability ...
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Article
Open AccessControl of maleic acid-propylene diepoxide hydrogel for 3D printing application for flexible tissue engineering scaffold with high resolution by end cap** and graft polymerization
Control of 3D printing of highly tough hydrogel inks with adequate printability, scaffold fidelity and mechanical properties are highly desirable for biomedical and tissue engineering applications. However, de...
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Article
The effects of BRL-50481 on ovalbumin-induced asthmatic lung inflammation exacerbated by co-exposure to Asian sand dust in the murine model
Asian sand dust (ASD), which mainly originates in China and Mongolia in the spring and blows into Korea, can exacerbate respiratory and immunological diseases. This study aims to observe effects of co-exposure...
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Article
Clinical outcomes of rectangular tunnel technique in posterior cruciate ligament reconstruction were comparable to the results of conventional round tunnel technique
To compare clinical outcomes between the conventional round and rectangular tunnel techniques in single-bundle posterior cruciate ligament (PCL) reconstruction.
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Article
Hevin–calcyon interaction promotes synaptic reorganization after brain injury
Hevin, also known as SPARC-like protein 1 (SPARCL1 or SC1), is a synaptogenic protein secreted by astrocytes and modulates the formation of glutamatergic synapses in the develo** brain by interacting with sy...
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Article
Hydrodynamic Ram Test of Composite T-Joint Structure
The response of composite T-joint specimens to hydrodynamic ram testing is investigated in this study. A hydrodynamic ram is one of the major manmade threats to aircraft structures, particularly to fuel system...
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Article
Open AccessAn antisite defect mechanism for room temperature ferroelectricity in orthoferrites
Single-phase multiferroic materials that allow the coexistence of ferroelectric and magnetic ordering above room temperature are highly desirable, motivating an ongoing search for mechanisms for unconventional...
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Article
Open AccessDevelopment of a miRNA-controlled dual-sensing system and its application for targeting miR-21 signaling in tumorigenesis
MicroRNAs (miRNAs) are considered to be strong prognostic markers and key therapeutic targets in human diseases, especially cancer. A sensitive monitoring platform for cancer-associated miRNA (oncomiR) action ...
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Article
Comparative cerebrospinal fluid metabolites profiling in glioma patients to predict malignant transformation and leptomeningeal metastasis with a potential for preventive personalized medicine
Glioma shows progression presenting as malignant transformation or leptomeningeal metastasis (LM). However, longitudinal biopsy of brain parenchyma is difficult due to its critical location, whereas cerebrospi...
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Article
Open AccessLipopolysaccharide administration for a mouse model of cerebellar ataxia with neuroinflammation
Most cerebellar ataxias (CAs) are incurable neurological disorders, resulting in a lack of voluntary control by inflamed or damaged cerebellum. Although CA can be either directly or indirectly related to cereb...
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Article
Open AccessARS2/MAGL signaling in glioblastoma stem cells promotes self-renewal and M2-like polarization of tumor-associated macrophages
The interplay between glioblastoma stem cells (GSCs) and tumor-associated macrophages (TAMs) promotes progression of glioblastoma multiforme (GBM). However, the detailed molecular mechanisms underlying the rel...
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Article
Effect of annealing temperature on the interfacial interaction of LiNi0.5Mn1.5O4 thin film cathode with stainless-steel substrate
LiNi0.5Mn1.5O4 thin films were coated on stainless steel substrates by radio-frequency sputtering at room temperature for a lithium-ion battery. The cathode films were post-annealed at 500, 600 and 700 °C to stud...
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Article
The novel resveratrol derivative 3,5-diethoxy-3′,4′-dihydroxy-trans-stilbene induces mitochondrial ROS-mediated ER stress and cell death in human hepatoma cells in vitro
Resveratrol (3,5,4′-trihydroxy-trans-stilbene) is a well-known polyphenol that is present in grapes, peanuts, pine seeds, and several other plants. Resveratrol exerts deleterious effects on various types of human...
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Article
Open AccessCLEC14a-HSP70-1A interaction regulates HSP70-1A-induced angiogenesis
CLEC14a (C-type lectin domain family 14 member) is a tumor endothelial cell marker protein that is known to play an important role in tumor angiogenesis, but the basic molecular mechanisms underlying this func...
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Article
Failure behavior of a composite T-joint subjected to hydrodynamic ram
The Hydrodynamic ram (HRAM) phenomenon is one of the main types of ballistic battle damages of a military aircraft and has great importance to airframe survivability design. The HRAM phenomenon occurs in aircr...
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Article
Failure prediction of composite T-joints for hydrodynamic ram test
The wing structure of an aircraft also served as a fuel tank containing fluid. The fuel tank and joint structure are made up of composite structures. Hydrodynamic ram (HRAM) effect occurs when the explosion or...
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Article
Open AccessAn extraordinary palaeontinid from the Triassic of Korea and its significance
A new, extraordinary palaeontinid Hallakkungis amisanus Nam, Wang & Szwedo, gen. et sp. nov., from the Upper Triassic of the Amisan Formation in Boryeong City, Korea is described. It is the first Palaeontinidae f...
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Article
Bird-mimetic Wing System of Flap**-wing Micro Air Vehicle with Autonomous Flight Control Capability
A micro air vehicle with a bird-mimetic up-down and twisting wing drive system was developed in this study. The Flap**-wing Micro Air Vehicle (FMAV), with a 50 cm wingspan and a double-crank drive system, pe...
