5 Result(s)
within
Jonathan P. Wisor
Neurosciences
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Article
Diurnal changes in perineuronal nets and parvalbumin neurons in the rat medial prefrontal cortex
Perineuronal nets (PNNs) surrounding fast-spiking, parvalbumin (PV) interneurons provide excitatory:inhibitory balance, which is impaired in several disorders associated with altered diurnal rhythms, yet few s...
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Chapter
Dopamine and Wakefulness: Pharmacology, Genetics, and Circuitry
Over the period of decades in the mid to late twentieth century, arousal-promoting functions were attributed to neuromodulators including serotonin, hypocretin, histamine, and noradrenaline. For some time, a r...
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Article
A metabolic–transcriptional network links sleep and cellular energetics in the brain
This review proposes a mechanistic link between cellular metabolic status, transcriptional regulatory changes and sleep. Sleep loss is associated with changes in cellular metabolic status in the brain. Metabol...
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Article
Sleep-active cells in the cerebral cortex and their role in slow-wave activity
We recently identified neurons in the cerebral cortex that become activated during sleep episodes with high slow-wave activity (SWA). The distinctive properties of these neurons are the ability to produce nitr...
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Article
Open AccessA role for cryptochromesin sleep regulation
The cryptochrome 1 and 2 genes (cry1 and cry2) are necessary for the generation of circadian rhythms, as mice lacking both of these genes (cry1,2-/-) lack circadian rhythms. We studied sleep in cry1,2-/- mice und...
