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  1. Article

    Open Access

    Screening and identification of lncRNAs in preadipocyte differentiation in sheep

    Studies of preadipocyte differentiation and fat deposition in sheep have mainly focused on functional genes, and with no emphasis placed on the role that long non-coding RNAs (lncRNAs) may have on the activity...

    Zhiyun Hao, **ayang **, Jon G. H. Hickford, Huitong Zhou… in Scientific Reports (2024)

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  2. No Access

    Article

    Identification of sequence variation in the oocyte-derived bone morphogenetic protein 15 (BMP15) gene (BMP15) associated with litter size in New Zealand sheep (Ovis aries) breeds

    Advances in the study of reproductive traits indicate that functional variation in fertility genes may be useful for improving sheep fertility. The aim of this study was to search for variation in the bone mor...

    Hamed Amirpour Najafabadi, Majid Khansefid… in Molecular Biology Reports (2021)

  3. No Access

    Article

    Variation in the KRTAP6-3 gene and its association with wool characteristics in Pakistani sheep breeds and breed-crosses

    This study investigated variation in the keratin-associated proteins gene, KRTAP6-3, in 5 Pakistani sheep breeds/crosses using polymerase chain reaction-single strand confirmation polymorphism (PCR-SSCP) analysis...

    Farman Ullah, Syed M. Jamal, Huitong Zhou… in Tropical Animal Health and Production (2020)

  4. Article

    Open Access

    Identification of four new gene members of the KAP6 gene family in sheep

    KAP6 is a high glycine-tyrosine keratin-associated protein (HGT-KAP) family. This family is thought to contain multiple genes. In this study, we used a KRTAP6 coding sequence to search the Ovine Genome (v3.1) and...

    Huitong Zhou, Hua Gong, Jiqing Wang, Jolon M. Dyer, Yuzhu Luo… in Scientific Reports (2016)

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  5. Article

    Open Access

    Effect of variation in ovine WFIKKN2 on growth traits appears to be gender-dependent

    WFIKKN2 may play a role in the regulation of muscle growth and development, but to date there have been no reports on the effect of variation in WFIKKN2 on growth and carcass traits in livestock. In this study, t...

    Jiqing Wang, Huitong Zhou, Qian Fang, **u Liu, Yuzhu Luo… in Scientific Reports (2015)

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  6. No Access

    Article

    Halplotypes of the ovine ADRB3 gene (ADRB3) and their association with post-weaning growth in New Zealand Suffolk sheep

    The β3-adrenergic receptor (ADRB3) regulates thermogenesis and lipolysis in brown and white adipose tissue. Previously, sixteen ovine ADRB3 haplotypes have been defined. In this study, the relationship between th...

    Guo Yang, Huitong Zhou, Rachel H. Forrest, Qian Fang… in Molecular Biology Reports (2013)

  7. No Access

    Article

    Ovine forkhead box class O 3 (FOXO3) gene variation and its association with lifespan

    FOXO3 is a member of the FOXO (forkhead box class O) transcription factor family and has roles in cell cycle control, apoptosis, neural and hematopoietic cell differentiation and DNA repair among other functio...

    Seung Ok Byun, Rachel H. Forrest, Huitong Zhou… in Molecular Biology Reports (2013)

  8. No Access

    Article

    Allelic variation in ovine fatty acid-binding protein (FABP4) gene

    The fatty acid-binding protein 4 (FABP4) plays a role in lipid metabolism and has been implicated in intra-cellular lipid transport. While FABP4 variation has been reported in some species, variation in the codin...

    Wei Yan, Huitong Zhou, Yuzhu Luo, Jiang Hu, Jon G. H. Hickford in Molecular Biology Reports (2012)

  9. No Access

    Article

    Identification of the ovine KAP11-1 gene (KRTAP11-1) and genetic variation in its coding sequence

    Keratin-associated proteins (KAPs) are a structural component of the wool fibre and form the matrix between the keratin intermediate filaments (KIFs). The gene encoding high sulphur-protein KAP11-1 has been id...

    Hua Gong, Huitong Zhou, Jolon M. Dyer, Jon G. H. Hickford in Molecular Biology Reports (2011)

  10. No Access

    Article

    Diversity of the glycine/tyrosine-rich keratin-associated protein 6 gene (KAP6) family in sheep

    Keratin-associated proteins (KAPs) are structural components of wool and variation in them may affect wool characteristics. In this study, we used PCR-SSCP to analyse the ovine KAP6 family which encodes glycine a...

    Hua Gong, Huitong Zhou, Jon G. H. Hickford in Molecular Biology Reports (2011)

  11. No Access

    Article

    Polymorphism of the ovine keratin-associated protein 1-4 gene (KRTAP1-4)

    Keratin-associated proteins (KAPs) are one of the main structural components of the wool fibre and form a semi-rigid matrix in which the keratin intermediate filaments are embedded. Variation in the KAP genes ...

    Hua Gong, Huitong Zhou, Jon G. H. Hickford in Molecular Biology Reports (2010)

  12. No Access

    Article

    Polymorphism of the bovine ADRB3 gene

    The β3-adrenergic receptor (ADRB3) is predominantly expressed in white and brown adipose tissue and mediates the lipolytic and thermogenic effects of high catecholamine concentrations. Variation in the ADRB3 gene...

    Jiang Hu, Huitong Zhou, Anna Smyth, Yuzhu Luo… in Molecular Biology Reports (2010)

  13. No Access

    Article

    Extensive Diversity of the ADRB3 Gene in Chinese Sheep Identified by PCR-SSCP

    The β3-adrenergic receptor (ADRB3) is the main mediator of the lipolytic and thermogenic effects of high catecholamine concentrations. Polymorphism in the ovine ADRB3 gene has been reported to be associated with ...

    Guo Yang, Huitong Zhou, Jiang Hu, Yuzhu Luo, Jon G. H. Hickford in Biochemical Genetics (2009)

  14. No Access

    Article

    Allelic Variation in the Porcine MYF5 Gene Detected by PCR–SSCP

    The MYF5 gene has been reported to be integral to muscle growth and development, and hence it has been considered as a candidate gene for meat selection programs in pig. To ascertain whether there was variation i...

    Sajee Kunhareang, Huitong Zhou, Jon G. H. Hickford in Molecular Biotechnology (2009)

  15. No Access

    Article

    Identification of Allelic Polymorphism in the Ovine Leptin Gene

    Leptin is an adipocyte-derived hormone/cytokine that influences the physiological control of numerous biological functions and links nutritional status with both neuroendocrine and immune functions. In livesto...

    Huitong Zhou, Jon G. H. Hickford, Hua Gong in Molecular Biotechnology (2009)

  16. No Access

    Article

    Polymorphism of the IGHA gene in sheep

    Genetic variation in immunoglobulin A, the most abundant immunoglobulin in mammalian cells, has not been reported in ruminants. In this study, variation in the immunoglobulin heavy alpha chain constant gene (IGHA

    Huitong Zhou, Jon G. H. Hickford, Qian Fang in Immunogenetics (2005)