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Posterior Urethral Valves Outcomes Prediction (PUVOP): a machine learning tool to predict clinically relevant outcomes in boys with posterior urethral valves
Early kidney and anatomic features may be predictive of future progression and need for additional procedures in patients with posterior urethral valve (PUV). The objective of this study was to use machine lea...
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Polystyrene microplastics induce an immunometabolic active state in macrophages
Anti-inflammatory and proinflammatory responses in macrophages are influenced by cellular metabolism. Macrophages are the primary phagocyte in mucosal environments (i.e., intestinal tract and lungs) acting as ...
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Urological Surgery in Children with Nephrolithiasis
The prevalence of nephrolithiasis in children is rising and the presentation of these patients can often be drastically different from that of adults. Special considerations including patient size must be take...
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Article
A Review of Low-Frequency EPR Technology for the Measurement of Brain pO2 and Oxidative Stress
EPR can uniquely measure paramagnetic species. Although commercial EPR was introduced in 1950s, the early studies were mostly restricted to chemicals in solution or cellular experiments using X-band EPR equipm...
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Biocatalytic reductive amination from discovery to commercial manufacturing applied to abrocitinib JAK1 inhibitor
Enzymatic reductive amination, being a direct, selective and green methodology, has attracted significant interest in a short period of time and is emerging as a powerful tool for the synthesis of chiral alkyl...
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Article
Nitric Oxide Interacts with Caveolin-1 to Facilitate Autophagy-Lysosome-Mediated Claudin-5 Degradation in Oxygen-Glucose Deprivation-Treated Endothelial Cells
Using in vitro oxygen-glucose deprivation (OGD) model, we have previously demonstrated that 2-h OGD induces rapid, caveolin-1-mediated dissociation of claudin-5 from the cellular cytoskeletal framework and qui...
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Open AccessDoes normobaric hyperoxia increase oxidative stress in acute ischemic stroke? A critical review of the literature
Stroke, one of the most debilitating cerebrovascular and nuerological diseases, is a serious life-threatening condition and a leading cause of long-term adult disability and brain damage, either directly or by...
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Development of Veterinary Laboratory Networks for Avian Influenza and Other Emerging Infectious Disease Control: The Southeast Asian Experience
The outbreak of highly pathogenic H5N1 avian influenza, with its international spread, confirmed that emerging infectious disease control must be underpinned by effective laboratory services. Laboratory result...
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Aneurysmal bone cyst within fibrous dysplasia of the anterior skull base: continued intracranial extension after endoscopic resections requiring craniofacial approach with free tissue transfer reconstruction
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The Price for “Free” Market Capitalism in Public Schools—or How much is Democracy Worth on the Open Market?
Ever since the Reagan administration published its report A Nation At Risk in 1983, the assumption has been that public schools are not performing at an acceptable economic or intellectual level. What is needed, ...
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Abstracts
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Reduced motion artifacts in medical imaging by adaptive spatio-temporal reconstruction
In this paper we introduce an algorithm for imaging a time varying object \(f(\vec x,t)\) , from its projections at d...
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The Denial of Social Experiment in Canadian Housing Policy before the Second World War
Canadian housing policies, unlike efforts in health care, have attained no noteworthy apotheosis, can claim no triumphant prophets of legislated social experiment, and have often expressed fiscal rather than s...
