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Open AccessQuantitative assessment of pulmonary artery occlusion using lung dynamic perfusion CT
Quantitative measurement of lung perfusion is a promising tool to evaluate lung pathophysiology as well as to assess disease severity and monitor treatment. However, this novel technique has not been adopted c...
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Open AccessThe feasibility of assessing swallowing physiology following prolonged intubation after cardiovascular surgery
Dysphagia following prolonged intubation after cardiovascular (CV) surgery is common occurring in 67% of patients; however, this population’s swallowing physiology has never been prospectively evaluated using ...
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Open AccessSex disparities in systemic sclerosis-associated pulmonary arterial hypertension: a cohort study
The impact of male sex as a determinant of health outcomes in systemic sclerosis-associated pulmonary arterial hypertension (SSc-PAH) is controversial. The primary objective of this study was to evaluate the e...
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Article
Dysphagia and Associated Risk Factors Following Extubation in Cardiovascular Surgical Patients
Following cardiovascular (CV) surgery, prolonged mechanical ventilation of >48 h increases dysphagia frequency over tenfold: 51 % compared to 3–4 % across all durations. Our primary objective was to identify d...
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Open AccessProphylactic anticoagulation to prevent venous thromboembolism in traumatic intracranial hemorrhage: a decision analysis
Patients with intracranial hemorrhage due to traumatic brain injury are at high risk of develo** venous thromboembolism including deep vein thrombosis (DVT) and pulmonary embolism (PE). Thus, there is a trad...
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The effects of vasopressin on acute kidney injury in septic shock
To compare the effects of vasopressin versus norepinephrine infusion on the outcome of kidney injury in septic shock.
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N-acetylcysteine for preventing acute kidney injury in cardiac surgery patients with pre-existing moderate renal insufficiency
N-acetylcysteine may prevent acute kidney injury after cardiac surgery. To determine if N-acetylcysteine warrants definitive evaluation in a large multicentre trial, we evaluated its effects on a surrogate out...
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Abstract
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Science Review: Vasopressin and the cardiovascular system part 2 – clinical physiology
Vasopressin is emerging as a rational therapy for vasodilatory shock states. In part 1 of the review we discussed the structure and function of the various vasopressin receptors. In part 2 we discuss vascular ...
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Science Review: Vasopressin and the cardiovascular system part 1 – receptor physiology
Vasopressin is emerging as a rational therapy for vasodilatory shock states. Unlike other vasoconstrictor agents, vasopressin also has vasodilatory properties. The goal of the present review is to explore the ...
