Skip to main content

3 Result(s)

within John H. McVey Remove this filter Medicine & Public Health Remove this filter

and

  1. Article

    Open Access

    The P2X7receptor is a candidate product of murine and human lupus susceptibility loci: a hypothesis and comparison of murine allelic products

    Systemic lupus erythematosus and its murine equivalent, modelled in the New Zealand Black and New Zealand White (NZB × NZW)F1 hybrid strain, are polygenic inflammatory diseases, probably reflecting an autoimmune ...

    James I Elliott, John H McVey, Christopher F Higgins in Arthritis Research & Therapy (2005)

    Download PDF (927 KB) View Article

  2. No Access

    Protocol

    Molecular Analysis in Factor XI Deficiency

    Factor XI (FXI) is the zymogen precursor of an active serine protease that participates in the contact phase of coagulation. Synthesized in the liver, it circulates in the plasma in a noncovalent complex with ...

    Karen M. Johnson, John H. McVey in Hemostasis and Thrombosis Protocols (1999)

  3. No Access

    Chapter

    Efficient Gene Transfer into Human Umbilical Vein Endothelial Cells Allows Functional Analysis of the Human Tissue Factor Gene Promoter

    Tissue factor (TF) is a cellular receptor and cofactor for factor VII/VIIa which inititates the blood coagulation cascade. We have investigated the role of 5′-flanking DNA sequences in regulating the expressio...

    Amit C. Nathwani, Karen M. Gale, Kieran D. Pemberton… in Vascular Endothelium (1996)