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  1. No Access

    Protocol

    Testing of General and Human-Associated Fecal Contamination in Waters

    qPCR has become increasingly popular for microbial water quality testing because it is faster, more specific, and more flexible than culture-based methods. However, qPCR method limitations such as quantificati...

    Yi** Cao, Meredith R. Raith, John F. Griffith in Digital PCR (2018)

  2. No Access

    Protocol

    The Next-Generation PCR-Based Quantification Method for Ambient Waters: Digital PCR

    Real-time quantitative PCR (qPCR) is increasingly being used for ambient water monitoring, but development of digital polymerase chain reaction (digital PCR) has the potential to further advance the use of mol...

    Yi** Cao, John F. Griffith, Stephen B. Weisberg in Marine Genomics (2016)

  3. No Access

    Article

    Comparison and Verification of Bacterial Water Quality Indicator Measurement Methods Using Ambient Coastal Water Samples

    More than 30 laboratories routinely monitor water along southern California's beaches for bacterial indicators of fecal contamination. Data from these efforts frequently are combined and compared even though t...

    John F. Griffith, Larissa A. Aumand in Environmental Monitoring and Assessment (2006)

  4. Article

    Prokaryotic and viral diversity patterns in marine plankton

    Prokaryotes and viruses play critical roles in marine ecosystems, where they are both highly abundant and active. Although early work on both prokaryotes and viruses revealed little of their diversity, molecu...

    Jed A. Fuhrman, John F. Griffith, Michael S. Schwalbach in Ecological Research (2002)

  5. Article

    1100 THE ARRHENIUS PLOT OF HEPATIC MICROSOMAL GLUCOSE-6-PHOSPHATASE ACTIVITY OF THE CONGENITALLY JAUNDICED (GUNN) RAT

    The failure of the Gunn rat to conjugate bilirubin results from either defective (or absent) bilirubin UDP-glucuronyl transferase or from a defect in the membrane environment of that enzyme. The latter possibi...

    Dennis P Black, Peter F Whitinqton, John F Griffith in Pediatric Research (1981)

  6. Article

    1139 PARATHYROID (PTH) AND ANTIDIURETIC HORMONE (ADH) IN REYE-JOHNSON SYNDROME (RJS)

    From the metabolic standpoint, several features of RJS implicate a role for cAMP in the pathophysiology of this disease. ↑ plasma cAMP is found in RJS to corroborate this possibility. In the presence of a norm...

    Ellen S Kano, Genaro M A Palmieri, Kathryn S Schwenzer in Pediatric Research (1981)

  7. Article

    EXPERIMENTAL HSV ENCEPHALITIS: EFFECTS OF TREATMENT WITH CYTOSINE ARABINOSIDE

    The effects of cytosine arabinoside (cytarabine) on survival and brain virus concentration were studied in groups of young mice with experimental herpes simplex virus (HSV) encephalitis. Toxic dosages of drug ...

    John F Griffith, Sandra Casagrande in Pediatric Research (1974)

  8. Article

    NORMAL ELECTROENCEPHALOGRAMS IN SUBACUTE SCLEROSING PANENCEPHALITIS (SSPE)

    Eleven cases of SSPE from the rural southeast were studied at Duke from 1968-73. Eight patients had a history of measles immunization and 5 of these reportedly had antecedent natural measles. The diagnosis was...

    Michael A Sisk, John F Griffith in Pediatric Research (1974)

  9. Article

    In vitro studies of post mortem neural tissue in subacute selerosing panecephalitis (SSPE)

    Brain and spinal cord from 2 cases of SSPE were obtained within one hour of death and cultures were established from multiple sites including frontal, temporal and parietal lobes, pons, cerebellum and cord. Th...

    John F Griffith, Samuel L Katz in Pediatric Research (1971)

  10. Article

    The effects of corticosteroids on experimental herpes simplex virus encephalitis

    This study examines the effects of corticosteroids on the ultimate survival, virus concentration and neuropathologic changes in mice with herpes simplex virus (HSV) encephalitis.

    John F Griffith, Samuel L Katz in Pediatric Research (1971)