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  1. Article

    Open Access

    Transiently expressed CRISPR/Cas9 induces wild-type dystrophin in vitro in DMD patient myoblasts carrying duplications

    Among the mutations arising in the DMD gene and causing Duchenne Muscular Dystrophy (DMD), 10–15% are multi-exon duplications. There are no current therapeutic approaches with the ability to excise large multi-ex...

    Veronica Pini, Virginie Mariot, Julie Dumonceaux, John Counsell in Scientific Reports (2022)