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  1. Article

    Open Access

    Transiently expressed CRISPR/Cas9 induces wild-type dystrophin in vitro in DMD patient myoblasts carrying duplications

    Among the mutations arising in the DMD gene and causing Duchenne Muscular Dystrophy (DMD), 10–15% are multi-exon duplications. There are no current therapeutic approaches with the ability to excise large multi-ex...

    Veronica Pini, Virginie Mariot, Julie Dumonceaux, John Counsell… in Scientific Reports (2022)

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    Chapter

    The Potential of Living Labs for Smart Heritage Building Adaptation

    This paper examines: smart buildings as part of ‘smart cities’; the particular challenges of heritage buildings; whether smart heritage buildings have any specific characteristics; the lack of data to inform a...

    John Counsell in Advanced Technologies for Sustainable Systems (2017)

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    Chapter and Conference Paper

    An Exploration of Design Alternatives Using Dynamic Thermal Modelling Software of an Exemplar, Affordable, Low Carbon Residential Development Constructed by a Registered Social Landlord in a Rural Area of Wales

    Pembrokeshire Housing Association (PHA) a registered social landlord, based in Haverfordwest, Wales, UK, have developed six low carbon houses to meet Code for Sustainable Homes (CfSH) level four, as part of an...

    Simon Hatherley, Wesley Cole, John Counsell… in Sustainability in Energy and Buildings (2013)

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    Chapter and Conference Paper

    In-Construction Testing of the Thermal Performance of Dwellings Using Thermography

    If the UK target for all new homes to be zero carbon by 2016 is to be achieved in practice, and not just in theory, considerable attention will need to be paid to closing the gap between designed and built per...

    Tim Taylor, John Littlewood, Steve Goodhew… in Sustainability in Energy and Buildings (2012)

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    Chapter and Conference Paper

    Visible Display of Automated Observation of Collaborative Workspaces

    Through the Facilities Innovation Research Programme, (www. facilitiesinnovation.co.uk) staff at the University of the West of England, Bristol and at Johnson Controls have been investigating systems that have...

    John Counsell, Marie-Cecile Puybaraud in Cooperative Design, Visualization, and Engineering (2006)

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    Chapter and Conference Paper

    Collaborative Web-Based 3D Masterplanning

    This paper describes an approach to empowering heterogeneous groups of people to share the tasks of digitising and updating buildings that may convey a credible sense of presence. We argue that more effective ...

    John Counsell, Steve Smith… in Cooperative Design, Visualization, and Eng… (2006)

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    Chapter and Conference Paper

    Public Digital Collaboration in Planning

    It is becoming increasingly important to European democratic governments to increase public participation. One of the areas that gives rise to significant public dissatisfaction and feelings of dis-empowerment...

    Stefanie Dühr, Nada Bates-Brkljac… in Cooperative Design, Visualization, and Eng… (2005)

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    Chapter and Conference Paper

    ’Under Construction’: The Potential of a Web Based Application in Managing and Maintaining Large Area Urban Modelling

    Staff in the Faculty of the Built Environment at the University of the West of England (UWE) have been engaged in 3D modelling urban areas since 1984. In the UK it will be mandatory that all local planning aut...

    John Counsell in Cooperative Design, Visualization, and Engineering (2004)