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Multi-ancestry genome-wide association analyses identify novel genetic mechanisms in rheumatoid arthritis

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  1. Article

    Open Access

    Genetic feature engineering enables characterisation of shared risk factors in immune-mediated diseases

    Genome-wide association studies (GWAS) have identified pervasive sharing of genetic architectures across multiple immune-mediated diseases (IMD). By learning the genetic basis of IMD risk from common diseases,...

    Oliver S. Burren, Guillermo Reales, Limy Wong, John Bowes, James C. Lee in Genome Medicine (2020)

  2. Article

    Correction: Corrigendum: Statistical colocalization of genetic risk variants for related autoimmune diseases in the context of common controls

    Nat. Genet. 47, 839–846 (2015); published online 8 June 2015; corrected after print 8 July 2015 In the version of this article initially published, the two panels in Figure 2 were presented in the incorrect or...

    Mary D Fortune, Hui Guo, Oliver Burren, Ellen Schofield, Neil M Walker in Nature Genetics (2015)

  3. Article

    Open Access

    Rare variation at the TNFAIP3 locus and susceptibility to rheumatoid arthritis

    Genome-wide association studies (GWAS) conducted using commercial single nucleotide polymorphisms (SNP) arrays have proven to be a powerful tool for the detection of common disease susceptibility variants. How...

    John Bowes, Robert Lawrence, Stephen Eyre, Kalliope Panoutsopoulou in Human Genetics (2010)