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Open AccessDiabetes mellitus in pregnancy across Canada
Contemporary estimates of diabetes mellitus (DM) rates in pregnancy are lacking in Canada. Accordingly, this study examined trends in the rates of type 1 (T1DM), type 2 (T2DM) and gestational (GDM) DM in Canad...
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Article
Open AccessABO and Rh blood groups and risk of infection: systematic review and meta-analysis
Persons with non-O and Rh-positive blood types are purported to be more susceptible to infection, including SARS-CoV-2, but there remains uncertainty about the degree to which this is so for both non-viral and...
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Open AccessPredicting adverse outcomes in pregnant patients positive for SARS-CoV-2: a machine learning approach- a retrospective cohort study
Pregnant people are particularly vulnerable to SARS-CoV-2 infection and to ensuing severe illness. Predicting adverse maternal and perinatal outcomes could aid clinicians in deciding on hospital admission and ...
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Twin pregnancy and severe maternal mental illness: a Canadian population-based cohort study
Twin pregnancy is a risk factor for postpartum depression and anxiety. Whether this translates into a higher risk of severe maternal mental illness in the short-term or long-term is unknown. This study was a p...
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Article
Pre-phototherapy total serum bilirubin levels in extremely preterm infants
Extremely preterm infants are prone to hyperbilirubinemia and its sequelae. Currently recommended thresholds for initiating phototherapy in these newborns are consensus-based (CB).
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Perinatal mental illness among women with disabilities: a population-based cohort study
To examine the risk of perinatal mental illness, including new-onset disorders and recurrent or ongoing use of mental health care, comparing women with physical, sensory, intellectual/developmental, and multip...
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Open AccessDevelopment and internal validation of a model predicting severe maternal morbidity using pre-conception and early pregnancy variables: a population-based study in Ontario, Canada
Improvement in the prediction and prevention of severe maternal morbidity (SMM) - a range of life-threatening conditions during pregnancy, at delivery or within 42 days postpartum - is a public health priority...
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Open AccessStillbirth in Canada: anachronistic definition and registration processes impede public health surveillance and clinical care
The archaic definition and registration processes for stillbirth currently prevalent in Canada impede both clinical care and public health. The situation is fraught because of definitional problems related to ...
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BMI and risk of gestational diabetes among women of South Asian and Chinese ethnicity: a population-based study
The aim of this study was to examine how BMI influences the association between Asian ethnicity and risk of gestational diabetes (GDM).
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Open AccessDiabetes after pregnancy: a study protocol for the derivation and validation of a risk prediction model for 5-year risk of diabetes following pregnancy
Pregnancy offers a unique opportunity to identify women at higher future risk of type 2 diabetes mellitus (DM). In pregnancy, a woman has greater engagement with the healthcare system, and certain conditions a...
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Open AccessA new record linkage for assessing infant mortality rates in Ontario, Canada
Infant mortality statistics for Canada have routinely omitted Ontario—Canada’s most populous province—as a high proportion of Vital Statistics infant death registrations could not be linked with their correspo...
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Open AccessGestational weight gain counselling practices among different antenatal health care providers: a qualitative grounded theory study
Inappropriate gestational weight gain in pregnancy may negatively impact health outcomes for mothers and babies. While optimal gestational weight gain is often not acheived, effective counselling by antenatal ...
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Open AccessPrediction of pre-eclampsia in nulliparous women using routinely collected maternal characteristics: a model development and validation study
Guidelines recommend identifying in early pregnancy women at elevated risk of pre-eclampsia. The aim of this study was to develop and validate a pre-eclampsia risk prediction model for nulliparous women attend...
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Open AccessVariability in intensive care unit admission among pregnant and postpartum women in Canada: a nationwide population-based observational study
Pregnancy-related critical illness results in approximately 300,000 deaths globally each year. The objective was to describe the variation in ICU admission and the contribution of patient- and hospital-based f...
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Incidence and risk factors for gestational diabetes mellitus in twin versus singleton pregnancies
To compare the incidence and risk factors for gestational diabetes mellitus (GDM) between women with twin and singleton pregnancies.
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Open AccessInfant feeding practices within a large electronic medical record database
The emerging adoption of the electronic medical record (EMR) in primary care enables clinicians and researchers to efficiently examine epidemiological trends in child health, including infant feeding practices.
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Reported Health Behaviour Changes after a Diagnosis of Gestational Diabetes Mellitus among Ethnic Minority Women Living in Canada
The aim of this cross-sectional study was to examine differences in health behaviours among ethnic minority and Caucasian women after a diagnosis of gestational diabetes mellitus (GDM). Data were derived from ...
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Visceral Adiposity in the First Half of Pregnancy in Association with Glucose, Lipid and Insulin Profiles in Later Pregnancy: A Cohort Study
Background Obesity is the most common risk factor in pregnancy but few studies have assessed the association of between visceral adiposity (VAT) depth in early to mild pregnancy and insul...
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Open AccessThe BRAzil MAGnesium (BRAMAG) trial: a randomized clinical trial of oral magnesium supplementation in pregnancy for the prevention of preterm birth and perinatal and maternal morbidity
Preterm birth is the leading cause of infant mortality globally, including Brazil. We will evaluate whether oral magnesium citrate reduces the risk of placental dysfunction and its negative consequences for bo...
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Open AccessAntenatal risk factors for peanut allergy in children
Prenatal factors may contribute to the development of peanut allergy. We evaluated the risk of childhood peanut allergy in association with pregnancy exposure to Rh immune globulin, folic acid and ingestion of...
