8 Result(s)
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Open AccessThe legacy of Malcolm Beverley Segal (1937–2019) on the science and fields concerned with choroid plexus and cerebrospinal fluid physiology
This article highlights the scientific achievements, professional career, and personal interactions of Malcolm B. Segal who passed away in July this year. Born in 1937 in Goodmayes, Essex, UK, Segal rose to th...
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Article
Open AccessThe quest for a better insight into physiology of fluids and barriers of the brain: the exemplary career of Joseph D. Fenstermacher
In June 2014 Dr. Joseph D. Fenstermacher celebrated his 80th birthday, which was honored by the symposium held in New London, NH, USA. This review discusses Fenstermacher’s contribution to the field of fluids ...
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CNS Barriers in Neurotrauma
Despite significant advances in designing neuroprotective therapies, multiple clinical trials in head trauma and spinal cord injury have produced mixed results. A better understanding of the pathophysiology of...
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Blood–Brain Barrier Pathophysiology in Traumatic Brain Injury
The blood–brain barrier (BBB) is formed by tightly connected cerebrovascular endothelial cells, but its normal function also depends on paracrine interactions between the brain endothelium and closely located ...
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Open AccessThe Adhesion GPCR GPR125 is specifically expressed in the choroid plexus and is upregulated following brain injury
GPR125 belongs to the family of Adhesion G protein-coupled receptors (GPCRs). A single copy of GPR125 was found in many vertebrate genomes. We also identified a Drosophila sequence, DmCG15744, which shares a comm...
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Open AccessExpression of junctional proteins in choroid plexus epithelial cell lines: a comparative study
There is an increasing interest in using choroid plexus (CP) epithelial cell lines to study the properties of the blood-cerebrospinal fluid barrier (BCSFB). Currently, there are three major CP-derived cell lin...
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Chapter
Vasopressin Gene Expression in Rat Choroid Plexus
Vasopressin (VP) levels in cerebrospinal fluid (CSF) change in response to physiological stimuli and under various pathological conditions. The sources of CSF VP have yet to be clarified, however. In the prese...
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Immunohistochemical localization of nitric oxide synthase in rat anterior choroidal artery, stromal blood microvessels, and choroid plexus epithelial cells
Nitric oxide (NO) has recently been shown to regulate blood flow to choroid plexus, a specialized brain structure responsible for production of most of cerebrospinal fluid. In the present study, we used a spec...
