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Article
Open AccessPresenilin E318G variant and Alzheimer’s disease risk: the Cache County study
Alzheimer's disease is the leading cause of dementia in the elderly and the third most common cause of death in the United States. A vast number of genes regulate Alzheimer’s disease, including Presenilin 1 (PSEN...
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Article
Open AccessPopulation substructure in Cache County, Utah: the Cache County study
Population stratification is a key concern for genetic association analyses. In addition, extreme homogeneity of ethnic origins of a population can make it difficult to interpret how genetic associations in th...
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Article
Open AccessMitochondrial genomic variation associated with higher mitochondrial copy number: the Cache County Study on Memory Health and Aging
The mitochondria are essential organelles and are the location of cellular respiration, which is responsible for the majority of ATP production. Each cell contains multiple mitochondria, and each mitochondrion...