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  1. No Access

    Article

    Lepr+ mesenchymal cells sense diet to modulate intestinal stem/progenitor cells via Leptin–Igf1 axis

    Diet can impact on gut health and disease by modulating intestinal stem cells (ISCs). However, it is largely unknown if and how the ISC niche responds to diet and influences ISC function. Here, we demonstrate ...

    Min Deng, Christian F. Guerrero-Juarez, **aole Sheng, Jiuzhi Xu, ** Wu… in Cell Research (2022)

  2. No Access

    Article

    The Msi1-mTOR pathway drives the pathogenesis of mammary and extramammary Paget’s disease

    Mammary and extramammary Paget’s Diseases (PD) are a malignant skin cancer characterized by the appearance of Paget cells. Although easily diagnosed, its pathogenesis remains unknown. Here, single-cell RNA-seq...

    Yongli Song, Christian F. Guerrero-Juarez, Zhongjian Chen, Yichen Tang… in Cell Research (2020)