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Article
Open AccessDevelopment of effective anti-influenza drugs: congeners and conjugates – a review
Influenza is a long-standing health problem. For treatment of seasonal flu and possible pandemic infections, there is a need to develop new anti-influenza drugs that have good bioavailability against a broad s...
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Article
Open AccessA chemical probe inhibitor targeting STAT1 restricts cancer stem cell traits and angiogenesis in colorectal cancer
Colorectal cancer (CRC) is a worldwide cancer with rising annual incidence. New medications for patients with CRC are still needed. Recently, fluorescent chemical probes have been developed for cancer imaging ...
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Article
Open AccessA synthetic pregnenolone analog promotes microtubule dynamics and neural development
Pregnenolone (P5) is a neurosteroid that promotes microtubule polymerization. It also reduces stress and negative symptoms of schizophrenia, promotes memory, as well as recovery from spinal cord injury. P5 is ...
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Article
Open AccessEngineered droplet-forming peptide as photocontrollable phase modulator for fused in sarcoma protein
The assembly and disassembly of biomolecular condensates are crucial for the subcellular compartmentalization of biomolecules in the control of cellular reactions. Recently, a correlation has been discovered b...
