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Article
Open AccessEnzyme engineering for functional lipids synthesis: recent advance and perspective
Functional lipids, primarily derived through the modification of natural lipids by various processes, are widely acknowledged for their potential to impart health benefits. In contrast to chemical methods for ...
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Article
Open AccessDirected evolution driving the generation of an efficient keratinase variant to facilitate the feather degradation
Keratinases can specifically degrade keratins, which widely exist in hair, horns, claws and human skin. There is a great interest in develo** keratinase to manage keratin waste generated by the poultry indus...
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Article
Engineering yeast metabolism for the discovery and production of polyamines and polyamine analogues
Structurally complex and diverse polyamines and polyamine analogues are potential therapeutics and agrochemicals that can address grand societal challenges, for example, healthy ageing and sustainable food pro...
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Article
Improving the biocatalytic performance of co-immobilized cells harboring nitrilase via addition of silica and calcium carbonate
To improve nicotinic acid (NA) yield and meet industrial application requirements of sodium alginate-polyvinyl alcohol (SA-PVA) immobilized cells of Pseudomonas putida mut-D3 harboring nitrilase, inorganic materi...
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Article
Phospholipase D engineering for improving the biocatalytic synthesis of phosphatidylserine
Phosphatidylserine is widely used in food, health, chemical and pharmaceutical industries. The phospholipase D-mediated green synthesis of phosphatidylserine has attracted substantial attention in recent years...
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Article
Open AccessProduction of fatty acid-derived oleochemicals and biofuels by synthetic yeast cell factories
Sustainable production of oleochemicals requires establishment of cell factory platform strains. The yeast Saccharomyces cerevisiae is an attractive cell factory as new strains can be rapidly implemented into exi...
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Article
Open AccessModular pathway rewiring of Saccharomyces cerevisiae enables high-level production of L-ornithine
Baker’s yeast Saccharomyces cerevisiae is an attractive cell factory for production of chemicals and biofuels. Many different products have been produced in this cell factory by reconstruction of heterologous bio...
