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  1. Article

    Open Access

    The genetic heterogeneity and mutational burden of engineered melanomas in zebrafish models

    Melanoma is the most deadly form of skin cancer. Expression of oncogenic BRAF or NRAS, which are frequently mutated in human melanomas, promote the formation of nevi but are not sufficient for tumorigenesis. Even...

    Jennifer Yen, Richard M White, David C Wedge, Peter Van Loo in Genome Biology (2013)

  2. Article

    Open Access

    Single-cell copy number variation detection

    Detection of chromosomal aberrations from a single cell by array comparative genomic hybridization (single-cell array CGH), instead of from a population of cells, is an emerging technique. However, such detect...

    Jiqiu Cheng, Evelyne Vanneste, Peter Konings, Thierry Voet in Genome Biology (2011)